Quinoxaline, 6-bromo-2,3-dimethyl-

Base Information

• Chemical Name: Quinoxaline, 6-bromo-2,3-dimethyl-
• CAS No.: 18470-23-0
• Molecular Formula: C10H9BrN2
• Molecular Weight: 237.099
• Hs Code.: 2933990090
• Mol file: 18470-23-0.mol

Synonyms:2,3-dimethyl-6-bromoquinoxaline;6-Brom-2,3-dimethylchinoxalin;6-bromo-2,3-dimethyl-quinoxaline;Quinoxaline,6-bromo-2,3-dimethyl;2,3-dimethyl-7-bromoquinoxaline;

Chemical Property of Quinoxaline, 6-bromo-2,3-dimethyl-

Chemical Property:

• PSA: 25.78000
• LogP: 3.00910

Purity/Quality:

99% ^*data from raw suppliers

6-Bromo-2,3-dimethylquinoxaline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Quinoxaline, 6-bromo-2,3-dimethyl-

There total 8 articles about Quinoxaline, 6-bromo-2,3-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

dimethylglyoxal (431-03-8) + 4-Bromo-benzene-1,2-diamine (1575-37-7) → 6-bromo-2,3-dimethylquinoxaline (18470-23-0)

Guidance literature:

In neat (no solvent); at 24.84 ℃;

DOI:10.1039/c5nj03282b

Reference yield: 93.0%

4-Bromo-2-nitroaniline (875-51-4) + dimethylglyoxal (431-03-8) → 6-bromo-2,3-dimethylquinoxaline (18470-23-0)

Guidance literature:

With indium; indium(III) chloride; In methanol; for 0.833333h; Reflux; Inert atmosphere;

DOI:10.1016/j.tet.2015.01.007

Reference yield: 82.0%

4-Bromo-2-nitroaniline (875-51-4) + 2.3-butanediol (513-85-9) → 6-bromo-2,3-dimethylquinoxaline (18470-23-0)

Guidance literature:

With sodium hydroxide; In toluene; at 120 ℃; for 3h; Inert atmosphere; Sealed tube; Green chemistry;

DOI:10.1021/acs.joc.0c02453

upstream raw materials:

dimethylglyoxal

4-Bromo-benzene-1,2-diamine

4-Bromo-2-nitroaniline

2,3-dimethylquinoxaline

Downstream raw materials:

2,3-dimethylquinoxaline

1,1-diphenyl-2-(3-methyl-2-quinoxalinyl)ethanol

2,3-dimethyl-6-[3-(piperidin-1-ylmethyl)phenyl]quinoxaline

Refernces

• 1、 -. "Quinoxaline compound containing triazine group, quinoxaline composition, electron transport material and electroluminescent device". Paragraph 0060-0062; 0066-0068. . Retrieved 2021/10/02.
• 2、 Chun, Simin,Hong, Junhwa,Hong, Suckchang,Lee, Seok Beom,Oh, Dong-Chan,Putta, Ramachandra Reddy. "Iron-catalyzed one-pot synthesis of quinoxalines: Transfer hydrogenative condensation of 2-nitroanilines with vicinal diols". . p. 18225 - 18230. Retrieved 2021/06/03.