1-{5-Fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl}ethan-1-one

Base Information

Chemical Name:1-{5-Fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl}ethan-1-one
CAS No.:5842-58-0
Molecular Formula:C₁₉H₂₂O₂
Molecular Weight:282.382
Hs Code.:
DSSTox Substance ID:DTXSID40386774
Wikidata:Q82180434

Synonyms:5842-58-0;1-[5-fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl]ethanone;1-{5-Fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl}ethan-1-one;DTXSID40386774;AB00098921-01;SR-01000532379;SR-01000532379-1

Suppliers and Price of 1-{5-Fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl}ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1-{5-Fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl}ethan-1-one

Chemical Property:

Vapor Pressure:3.57E-13mmHg at 25°C
Boiling Point:573.8°C at 760 mmHg
Flash Point:300.8°C
Density:1.292g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:389.15509786
Heavy Atom Count:28
Complexity:580

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1C(=O)C)F)N2CCN(CC2)C3=C(C=C(C(=C3)C)[N+](=O)[O-])F

Technology Process of 1-{5-Fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl}ethan-1-one

There total 7 articles about 1-{5-Fluoro-4-[4-(2-fluoro-5-methyl-4-nitrophenyl)piperazin-1-yl]-2-methylphenyl}ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13524-74-8
2-methyl-1-phenoxy-2-propanol

: 5842-58-0
1-(1-Hydroxy-1-phenyl-ethyl)-2,2-dimethyl-3-phenoxy-cyclopropan

Guidance literature:: Multi-step reaction with 5 steps

1: SOCl₂, Py

2: KOH

3: copper-powder

4: MeLi / diethyl ether

5: diethyl ether

With pyridine; potassium hydroxide; thionyl chloride; methyllithium; copper; In diethyl ether;

Reference yield:

: 5820-22-4
methylallyl phenyl ether

: 5842-58-0
1-(1-Hydroxy-1-phenyl-ethyl)-2,2-dimethyl-3-phenoxy-cyclopropan

Guidance literature:: Multi-step reaction with 4 steps

1: KOtBu, tBuOH

2: copper-powder

3: MeLi / diethyl ether

4: diethyl ether

With potassium tert-butylate; methyllithium; copper; tert-butyl alcohol; In diethyl ether;

Reference yield:

: 5820-20-2
((2-methylprop-1-en-1-yl)oxy)benzene

: 5842-58-0
1-(1-Hydroxy-1-phenyl-ethyl)-2,2-dimethyl-3-phenoxy-cyclopropan

Guidance literature:: Multi-step reaction with 3 steps

1: copper-powder

2: MeLi / diethyl ether

3: diethyl ether

With methyllithium; copper; In diethyl ether;