2-Methylbenzenesulfonohydrazide

Base Information

• Chemical Name: 2-Methylbenzenesulfonohydrazide
• CAS No.: 18684-09-8
• Molecular Formula: C7H10N2O2S
• Molecular Weight: 186.235
• DSSTox Substance ID: DTXSID20467595
• Wikidata: Q82294616
• Mol file: 18684-09-8.mol

Synonyms:2-methylbenzenesulfonohydrazide;18684-09-8;toluenesulfonhydrazide;2-Methylbenzene-1-sulfonohydrazide;1342693-27-9;STK331035;SCHEMBL420849;DTXSID20467595;OCVODYGWTBCBRL-UHFFFAOYSA-N;AKOS005438716;EN300-7832014

Chemical Property of 2-Methylbenzenesulfonohydrazide

Chemical Property:

• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 186.04629874
• Heavy Atom Count: 12
• Complexity: 232

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1S(=O)(=O)NN

Technology Process of 2-Methylbenzenesulfonohydrazide

There total 2 articles about 2-Methylbenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

Toluene-2-sulfonyl chloride (133-59-5) → toluene-sulphonic acid hydrazide (18684-09-8)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;

DOI:10.1039/c4cc05237d

Reference yield:

→ 4-{N-[α-(4-methyl-phenyl)-2-piperidino-benzyl]-aminocarbonylmethyl}-benzaldehyde + toluene-sulphonic acid hydrazide (18684-09-8)

Guidance literature:

Reference yield: 97.0%

toluene-sulphonic acid hydrazide (18684-09-8) + acetylacetone (123-54-6,81235-32-7) → 3,5-dimethyl-1,4-bis(o-tolylsulfonyl)-1H-pyrazole (1613250-56-8)

Guidance literature:

With tert.-butylhydroperoxide; cobalt(II) diacetate tetrahydrate; tetra-(n-butyl)ammonium iodide; In ethyl acetate; at 70 ℃; for 2h;

upstream raw materials:

Toluene-2-sulfonyl chloride

Downstream raw materials:

1,3,7-trimethyl-8-(o-tolyl)-xanthine

2-(2-methylphenyl)-1,3-benzoxazole

5-methyl-2-(2-methylphenyl)-1,3-benzoxazole

4-(2-methylphenyl)butan-2-one