3-(2-Chlorophenyl)-5-phenyl-1H-pyrazole

Base Information

Chemical Name:3-(2-Chlorophenyl)-5-phenyl-1H-pyrazole
CAS No.:187343-52-8
Molecular Formula:C₁₅H₁₁ClN₂
Molecular Weight:254.719
Hs Code.:
DSSTox Substance ID:DTXSID50468434
Nikkaji Number:J2.308.099K,J3.088.594E
Wikidata:Q82295626

Synonyms:3-(2-Chlorophenyl)-5-phenyl-1H-pyrazole;187343-52-8;5-(2-chlorophenyl)-3-phenyl-1H-pyrazole;SCHEMBL8888588;DTXSID50468434;3-(2-chlorophenyl)-5-phenylpyrazol

Suppliers and Price of 3-(2-Chlorophenyl)-5-phenyl-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(2-Chlorophenyl)-5-phenyl-1H-pyrazole

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:254.0610761
Heavy Atom Count:18
Complexity:265

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NNC(=C2)C3=CC=CC=C3Cl

Technology Process of 3-(2-Chlorophenyl)-5-phenyl-1H-pyrazole

There total 3 articles about 3-(2-Chlorophenyl)-5-phenyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₁₉ClN₂O₂S

: 187343-52-8
3-(2-chlorophenyl)-5-phenyl-1H-pyrazole

Guidance literature:: With potassium carbonate; In acetonitrile; at 25 ℃; Reagent/catalyst; Irradiation;
DOI:10.1002/adsc.201701200

Reference yield:

: 536-74-3
phenylacetylene

: 107135-19-3
N’-(2-chlorobenzylidene)-4-methylbenzenesulfonohydrazide

: 187343-52-8
3-(2-chlorophenyl)-5-phenyl-1H-pyrazole

Guidance literature:: N’-(2-chlorobenzylidene)-4-methylbenzenesulfonohydrazide; With sodium ethanolate; In toluene; at 20 ℃; for 0.25h;

phenylacetylene; In toluene; at 90 ℃; for 12h; regioselective reaction;
DOI:10.1055/s-0031-1290772

Reference yield:

: 89-98-5
2-chloro-benzaldehyde

: 187343-52-8
3-(2-chlorophenyl)-5-phenyl-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene / 1.58 h / 20 - 50 °C

2.1: sodium ethanolate / toluene / 0.25 h / 20 °C

2.2: 12 h / 90 °C

With sodium ethanolate; In toluene;
DOI:10.1055/s-0031-1290772