2-methyl-1-[(2S,3R)-3-phenyloxiran-2-yl]propan-1-one

Base Information

Chemical Name:2-methyl-1-[(2S,3R)-3-phenyloxiran-2-yl]propan-1-one
CAS No.:187837-40-7
Molecular Formula:C12H14O2
Molecular Weight:190.242
Hs Code.:
DSSTox Substance ID:DTXSID50548725
Nikkaji Number:J591.916I
Wikidata:Q82427531

Synonyms:187837-40-7;2-methyl-1-[(2S,3R)-3-phenyloxiran-2-yl]propan-1-one;DTXSID50548725

Suppliers and Price of 2-methyl-1-[(2S,3R)-3-phenyloxiran-2-yl]propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-methyl-1-[(2S,3R)-3-phenyloxiran-2-yl]propan-1-one

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:190.099379685
Heavy Atom Count:14
Complexity:216

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(=O)C1C(O1)C2=CC=CC=C2
Isomeric SMILES:CC(C)C(=O)[C@@H]1[C@H](O1)C2=CC=CC=C2

Technology Process of 2-methyl-1-[(2S,3R)-3-phenyloxiran-2-yl]propan-1-one

There total 2 articles about 2-methyl-1-[(2S,3R)-3-phenyloxiran-2-yl]propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 3160-32-5,5773-41-1,10596-48-2
(1E)-4-methyl-1-phenylpent-1-en-3-one

: 187837-40-7
trans-(1R,2S)-1,2-epoxy-4-methyl-1-phenylpentan-3-one

Guidance literature:: With Cumene hydroperoxide; 4 A molecular sieve; tri(4-fluorophenyl)phosphine oxide; lanthanum(III) isopropoxide; (R)-1,1'-Bi-2-naphthol; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1039/b405882h

Reference yield:

: 3160-32-5,5773-41-1,10596-48-2
(1E)-4-methyl-1-phenylpent-1-en-3-one

: 187837-40-7
trans-(1R,2S)-1,2-epoxy-4-methyl-1-phenylpentan-3-one

: 177314-50-0
trans-(1S,2R)-1,2-epoxy-4-methyl-1-phenylpentan-3-one

Guidance literature:: With tert.-butylhydroperoxide; Yb-3-hydroxymethyl-BINOL; In tetrahydrofuran; toluene; for 159h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
DOI:10.1021/ja964037o