ε-Aminocaproic Acid Hydrochloride

Base Information

• Chemical Name: ε-Aminocaproic Acid Hydrochloride
• CAS No.: 4321-58-8
• Molecular Formula: C6H13NO2
• Molecular Weight: 167.636
• Hs Code.: 2923900090
• Mol file: 4321-58-8.mol

Synonyms:6-aminohexanoic acid,hydrochloride;

Chemical Property of ε-Aminocaproic Acid Hydrochloride

Chemical Property:

• Melting Point: 128-129°
• PSA: 63.32000
• LogP: 2.09240
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

6-AminohexanoicAcidHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: ε-AMinocaproic Acid Hydrochloride can be used in the preparatiom of esters of 6-aminohexanoic acid

Technology Process of ε-Aminocaproic Acid Hydrochloride

There total 8 articles about ε-Aminocaproic Acid Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

caprolactam (105-60-2,9012-16-2) → 6-aminohexanoic acid hydrochloride (4321-58-8)

Guidance literature:

With hydrogenchloride; water; at 20 - 90 ℃; for 15h; Inert atmosphere;

Reference yield: 98.0%

methyl 6-isocyanatohexanoate (29640-13-9) → 6-aminohexanoic acid hydrochloride (4321-58-8)

Guidance literature:

With hydrogenchloride; at 100 ℃; for 24h;

Reference yield: 97.0%

6-(Ethoxycarbonylamino)hexansaeure-ethylester (5180-73-4) → 6-aminohexanoic acid hydrochloride (4321-58-8)

Guidance literature:

With hydrogenchloride; formic acid; In water; at 125 ℃; for 24h;

upstream raw materials:

methyl 6-isocyanatohexanoate

6-methoxycarbonylaminohexanoic acid methyl ester

6-(Ethoxycarbonylamino)hexansaeure-ethylester

6-aminohexanoic acid

Downstream raw materials:

6-aminohexanoic acid

6-<3-(4-Ethoxy-phenyl)-ureido>-hexansaeure-

6-(3-Phenyl-ureido)-hexansaeure-anilid

N-Methyl-6-isocyanato-hexansaeure-anilid

Refernces

• 1、 Rademeyer,Van Der Westhuizen. "Salts of 4-aminobutyric acid and 6-aminohexanoic acid behaving as molecular Velcro". . p. 6821 - 6836. Retrieved 2017/11/27.
• 2、 Tommasi, Sara,Zanato, Chiara,Carabeo, Rey,Mangoni, Arduino A.,Dall'Angelo, Sergio,Zanda, Matteo. "An Efficient Route to N-Monosubstituted Guanidino-Lactams". . p. 3067 - 3078. Retrieved 2015/09/28.