Methyl 2-acetamido-3-(dimethylamino)acrylate

Base Information

• Chemical Name: Methyl 2-acetamido-3-(dimethylamino)acrylate
• CAS No.: 188561-56-0
• Molecular Formula: C8H14N2O3
• Molecular Weight: 186.20800
• European Community (EC) Number: 844-919-2
• Mol file: 188561-56-0.mol

Synonyms:188561-56-0;Methyl 2-acetamido-3-(dimethylamino)acrylate

Chemical Property of Methyl 2-acetamido-3-(dimethylamino)acrylate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 334.281oC at 760 mmHg
• Flash Point: 155.968oC
• PSA: 58.64000
• Density: 1.091g/cm3
• LogP: 0.08940
• Storage Temp.: 2-8°C
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 186.10044231
• Heavy Atom Count: 13
• Complexity: 234

Purity/Quality:

98%min ^*data from raw suppliers

methyl(2E)-3-(dimethylamino)-2-acetamidoprop-2-enoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC(=CN(C)C)C(=O)OC

Technology Process of Methyl 2-acetamido-3-(dimethylamino)acrylate

There total 1 articles about Methyl 2-acetamido-3-(dimethylamino)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[(dimethylamino)methylene]-2-methyl-5(4H)-oxazolone (188663-05-0) → C8H14N2O3 (188561-56-0)

Guidance literature:

With methanol; sodium hydroxide;

DOI:10.1021/op300128c

Reference yield:

C8H14N2O3 (188561-56-0) → methyl 5-methyl-1,2,4-oxadiazole-3-carboxylate (19703-94-7)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water;

DOI:10.1021/op300128c

upstream raw materials:

4-[(dimethylamino)methylene]-2-methyl-5(4H)-oxazolone

Downstream raw materials:

methyl 5-methyl-1,2,4-oxadiazole-3-carboxylate

Refernces