4-Chloro-3-ethyl-2-methylquinoline

Base Information

Chemical Name:4-Chloro-3-ethyl-2-methylquinoline
CAS No.:1888-02-4
Molecular Formula:C12H12ClN
Molecular Weight:205.68300
Hs Code.:
DSSTox Substance ID:DTXSID501298239

Synonyms:4-chloro-3-ethyl-2-methylquinoline;1888-02-4;SCHEMBL7128183;DTXSID501298239;BAA88802;AKOS010226628;CCG-321337;EN300-127697;SR-01000315265;SR-01000315265-1;Z728804020

Suppliers and Price of 4-Chloro-3-ethyl-2-methylquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloro-3-ethyl-2-methylquinoline
100mg
$ 265.00

American Custom Chemicals Corporation
4-CHLORO-3-ETHYL-2-METHYLQUINOLINE 95.00%
5MG
$ 502.54

AK Scientific
4-Chloro-3-ethyl-2-methylquinoline
10g
$ 2997.00

Total 6 raw suppliers

Chemical Property of 4-Chloro-3-ethyl-2-methylquinoline

Chemical Property:

Melting Point:34-36 °C
Boiling Point:294.8±35.0 °C(Predicted)
PSA：12.89000
Density:1.156±0.06 g/cm3(Predicted)
LogP:3.75900
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:205.0658271
Heavy Atom Count:14
Complexity:195

Purity/Quality:

99% ^*data from raw suppliers

4-chloro-3-ethyl-2-methylquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(C2=CC=CC=C2N=C1C)Cl

Technology Process of 4-Chloro-3-ethyl-2-methylquinoline

There total 4 articles about 4-Chloro-3-ethyl-2-methylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1888-01-3
3-ethyl-2-methylquinolin-4-ol

: 1888-02-4
4-chloro-3-ethyl-2-methylquinoline

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; at 80 ℃; for 1h;
DOI:10.1021/jm060262x

Reference yield:

: 342896-03-1
2-Ethyl-3-phenyliminobuttersaeureethylester

: 1888-02-4
4-chloro-3-ethyl-2-methylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 3.31 g / diphenyl ether / 1 h / 250 °C

2: 2.92 g / thionyl chloride / dimethylformamide / 1 h / 80 °C

With thionyl chloride; In diphenylether; N,N-dimethyl-formamide;
DOI:10.1021/jm060262x

Reference yield:

: 62-53-3
aniline

: 1888-02-4
4-chloro-3-ethyl-2-methylquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: p-TsOH*H₂O / toluene / Heating

2: 3.31 g / diphenyl ether / 1 h / 250 °C

3: 2.92 g / thionyl chloride / dimethylformamide / 1 h / 80 °C

With thionyl chloride; toluene-4-sulfonic acid; In diphenylether; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm060262x