Technology Process of Serine, N-[3-(2-iodophenyl)propyl]-, methyl ester
There total 7 articles about Serine, N-[3-(2-iodophenyl)propyl]-, methyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium cyanoborohydride;
In
isopropyl alcohol;
for 14h;
Yield given;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 2 steps
2: NaBH3CN
With
sodium cyanoborohydride;
DOI:10.1055/s-1999-3088
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 92 percent / NaH / tetrahydrofuran / 1.) r.t., 30 min, 2.) r.t., 19 h
2: 77 percent / LiBEt3H / tetrahydrofuran / 1.) -78 deg C, 1 h, 2.) r.t., 18 h
3: 1.) DMSO, (COCl)2, 2.) Et3N / 1.) CH2Cl2, -60 deg C, 20 min, 2.) -60 deg C, 10 min
4: CH3COOK, 3 Angstroem molecular sieves / propan-2-ol / 1.) r.t., 15 min, 2.) r.t., 40 min
5: NaBH3CN / propan-2-ol / 14 h / Ambient temperature
With
oxalyl dichloride; 3 A molecular sieve; potassium acetate; sodium hydride; lithium triethylborohydride; sodium cyanoborohydride; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; isopropyl alcohol;
![3-Hydroxy-2-[3-(2-iodo-phenyl)-prop-(E)-ylideneamino]-propionic acid methyl ester](/Databaselist/images/loading.webp)
