2-Iodo-3,4-dimethoxybenzoic acid

Base Information

Chemical Name:2-Iodo-3,4-dimethoxybenzoic acid
CAS No.:6335-18-8
Molecular Formula:C9H9IO4
Molecular Weight:308.073
Hs Code.:
NSC Number:25375
DSSTox Substance ID:DTXSID10282299
Nikkaji Number:J2.644.759C
Wikidata:Q82016537

Synonyms:2-iodo-3,4-dimethoxybenzoic acid;6335-18-8;NSC25375;SCHEMBL3780281;2-iodo-3,4-dimethoxybenzoicacid;DTXSID10282299;NSC-25375

Suppliers and Price of 2-Iodo-3,4-dimethoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Iodo-3,4-dimethoxybenzoic acid

Chemical Property:

Vapor Pressure:3.92E-06mmHg at 25°C
Boiling Point:370.2°C at 760 mmHg
Flash Point:177.7°C
Density:1.79g/cm³
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:307.95456
Heavy Atom Count:14
Complexity:209

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)C(=O)O)I)OC

Technology Process of 2-Iodo-3,4-dimethoxybenzoic acid

There total 5 articles about 2-Iodo-3,4-dimethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 138490-95-6
2-iodo-3,4-dimethoxybenzaldehyde

: 6335-18-8
2-iodo-3,4-dimethoxybenzoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate dihydrate; dihydrogen peroxide; In water; acetonitrile; at 0 ℃; for 4h;
DOI:10.3987/COM-15-S(T)56

Reference yield: 55.0%

: 93-07-2
Veratric acid

: 6335-18-8
2-iodo-3,4-dimethoxybenzoic acid

Guidance literature:: Veratric acid; With n-butyllithium; 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; hexane; at -78 - 0 ℃;

With iodine; In tetrahydrofuran; hexane; for 1h; Further stages.; Heating;
DOI:10.1016/j.tet.2008.08.086

Reference yield:

: 138490-94-5
2-iodoisovanillin

: 6335-18-8
2-iodo-3,4-dimethoxybenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 1 h / Reflux

2: dihydrogen peroxide; sodium dihydrogenphosphate dihydrate; sodium chlorite / water; acetonitrile / 4 h / 0 °C

With sodium chlorite; sodium dihydrogenphosphate dihydrate; dihydrogen peroxide; potassium carbonate; In water; acetone; acetonitrile;
DOI:10.3987/COM-15-S(T)56