Benzoic acid, 4-(hydroxymethyl)-2-iodo-, methyl ester

Base Information

Chemical Name:Benzoic acid, 4-(hydroxymethyl)-2-iodo-, methyl ester
CAS No.:191104-99-1
Molecular Formula:C9H9IO3
Molecular Weight:292.073
Hs Code.:
Mol file:191104-99-1.mol

Synonyms:methyl-4-hydroxymethyl-2-iodo benzoate;methyl 4-hydroxymethyl-2-iodobenzoate;4-Hydroxymethyl-2-iodo-benzoic acid methyl ester;

Suppliers and Price of Benzoic acid, 4-(hydroxymethyl)-2-iodo-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzoic acid, 4-(hydroxymethyl)-2-iodo-, methyl ester

Chemical Property:

PSA：46.53000
LogP:1.57010

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzoic acid, 4-(hydroxymethyl)-2-iodo-, methyl ester

There total 4 articles about Benzoic acid, 4-(hydroxymethyl)-2-iodo-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 299173-24-3
[3-iodo-4-(methoxycarbonyl)]benzoic acid

: 191104-99-1
methyl 4-(hydroxymethyl)-2-iodobenzoate

Guidance literature:: With borane-THF; In tetrahydrofuran; at 0 ℃; for 30h;
DOI:10.3390/molecules25133058

Reference yield:

: 5372-81-6
dimethyl aminoterephthalate

: 191104-99-1
methyl 4-(hydroxymethyl)-2-iodobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 39 percent / DIBAL / tetrahydrofuran; diethyl ether / 4 h / -78 - 0 °C

2: 1.) 3 N H₂SO₄, NaNO₂, 2.) urea, KI / 1.) acetone, -15 deg C, 2.) acetone, RT, 2 h

With sulfuric acid; diisobutylaluminium hydride; urea; potassium iodide; sodium nitrite; In tetrahydrofuran; diethyl ether;
DOI:10.1021/jm980298s

Reference yield:

: 133728-31-1
methyl 2-amino-4-(hydroxymethyl)benzoate

: 191104-99-1
methyl 4-(hydroxymethyl)-2-iodobenzoate

Guidance literature:: With sulfuric acid; urea; potassium iodide; sodium nitrite; Yield given; Multistep reaction; 1.) acetone, -15 deg C, 2.) acetone, RT, 2 h;
DOI:10.1021/jm980298s