1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one

Base Information

• Chemical Name: 1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one
• CAS No.: 89108-58-7
• Molecular Formula: C19H16N2O3
• Molecular Weight: 320.348
• Hs Code.: 2933990090
• Mol file: 89108-58-7.mol

Synonyms:1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one;Sch 33303

Chemical Property of 1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one

Chemical Property:

• Vapor Pressure: 7.2E-10mmHg at 25°C
• Boiling Point: 493.2°C at 760 mmHg
• Flash Point: 252.1°C
• PSA: 61.19000
• Density: 1.28g/cm³
• LogP: 3.34410

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one

There total 2 articles about 1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

acetic anhydride (108-24-7) + 1-phenyl-4-(allyloxy)-1,8-naphthyridin-2(1H)-one (89109-18-2) → 4-acetyloxy-1-phenyl-3-(2-propenyl)-1,8-naphthyridin-2(1H)-one (89108-58-7)

Guidance literature:

for 4h; Heating;

DOI:10.1021/jm00119a010

Reference yield:

1-phenyl-4-(allyloxy)-1,8-naphthyridin-2(1H)-one (89109-18-2) → 4-acetyloxy-1-phenyl-3-(2-propenyl)-1,8-naphthyridin-2(1H)-one (89108-58-7)

Guidance literature:

With acetic anhydride;

Reference yield: 93.0%

4-acetyloxy-1-phenyl-3-(2-propenyl)-1,8-naphthyridin-2(1H)-one (89108-58-7) → 1-phenyl-3-(2-propenyl)-4-hydroxy-1,8-naphthyridin-2(1H)-one (89108-63-4)

Guidance literature:

With sodium hydroxide; In ethanol; Ambient temperature;

DOI:10.1021/jm00119a010

upstream raw materials:

acetic anhydride

1-phenyl-4-(allyloxy)-1,8-naphthyridin-2(1H)-one

Downstream raw materials:

1-phenyl-3-(2-propenyl)-4-hydroxy-1,8-naphthyridin-2(1H)-one

2-(bromomethyl)-3,9-dihydro-9-phenyl-furo(2,3-b)-1,8-naphthyridin-4(2H)-one