N-(2,6-Dimethylphenyl)-4-(phenylmethyl)-1-piperazineacetamide

Base Information

• Chemical Name: N-(2,6-Dimethylphenyl)-4-(phenylmethyl)-1-piperazineacetamide
• CAS No.: 55340-20-0
• Molecular Formula: C₂₁H₂₇N₃O
• Molecular Weight: 337.465
• DSSTox Substance ID: DTXSID001180578
• Mol file: 55340-20-0.mol

Synonyms:SCHEMBL6277857;DTXSID001180578;N-(2,6-Dimethylphenyl)-4-(phenylmethyl)-1-piperazineacetamide;AKOS003974381;55340-20-0;Z46172036

Chemical Property of N-(2,6-Dimethylphenyl)-4-(phenylmethyl)-1-piperazineacetamide

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 337.215412493
• Heavy Atom Count: 25
• Complexity: 403

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC3=CC=CC=C3

Technology Process of N-(2,6-Dimethylphenyl)-4-(phenylmethyl)-1-piperazineacetamide

There total 1 articles about N-(2,6-Dimethylphenyl)-4-(phenylmethyl)-1-piperazineacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

→ 2-(4-benzylpiperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide (55340-20-0)

Guidance literature:

With borane-ammonia complex; C₁₆H₂₉Cl₂CoN₂P; at 25 ℃; for 13h; Inert atmosphere; Schlenk technique;

Refernces

• 1、 -. "SUBSTITUTED ACETANILIDES AND BENZAMIDES FOR THE TREATMENT OF ASTHMA AND PULMONARY INFLAMMATION". Page/Page column 61. . Retrieved 2008/06/13.