Benzene, 1,2-dichloro-3,4,5,6-tetramethyl-

Base Information

• Chemical Name: Benzene, 1,2-dichloro-3,4,5,6-tetramethyl-
• CAS No.: 19219-82-0
• Molecular Formula: C10H12Cl2
• Molecular Weight: 203.111
• European Community (EC) Number: 654-900-9
• DSSTox Substance ID: DTXSID40400661
• Nikkaji Number: J1.591.923J
• Wikidata: Q82203670
• Mol file: 19219-82-0.mol

Synonyms:Benzene, 1,2-dichloro-3,4,5,6-tetramethyl-;19219-82-0;1,2-dichloro-3,4,5,6-tetramethyl-benzene;1,2-dichlorotetramethylbenzene;SCHEMBL10584467;DTXSID40400661;Tetramethyl-1,2-phenylene dichloride;AKOS024323194;1,2,3,4-Tetramethyl-5,6-dichlorbenzol

Chemical Property of Benzene, 1,2-dichloro-3,4,5,6-tetramethyl-

Chemical Property:

• Vapor Pressure: 0.0041mmHg at 25°C
• Boiling Point: 288.2oC at 760 mmHg
• Flash Point: 123.8oC
• PSA: 0.00000
• Density: 1.138g/cm3
• LogP: 4.22700
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 202.0316058
• Heavy Atom Count: 12
• Complexity: 140

Purity/Quality:

99% ^*data from raw suppliers

1,2-DICHLORO-3,4,5,6-TETRAMETHYL-BENZENE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=C(C(=C1C)Cl)Cl)C)C

Technology Process of Benzene, 1,2-dichloro-3,4,5,6-tetramethyl-

There total 2 articles about Benzene, 1,2-dichloro-3,4,5,6-tetramethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,2,3,4-Tetramethylbenzene (488-23-3) → 1,2,3,4-tetramethyl-2,5-dichlorobenzene (19219-82-0)

Guidance literature:

With benzyltrimethylazanium tetrachloro-λ³-iodanuide; In acetic acid; for 20h; Ambient temperature;

DOI:10.1246/bcsj.62.2096

Reference yield: 95.0%

1,2-dichloro-3,4,5,6-tetrabromobenzene (13075-03-1) + dimethyl sulfate (77-78-1) → 1,2,3,4-tetramethyl-2,5-dichlorobenzene (19219-82-0)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0040-4039(00)94184-4

Reference yield: 71.0%

1,2,3,4-tetramethyl-2,5-dichlorobenzene (19219-82-0) → 5,6-dichlorobenzene-1,2,3,4-tetracarboxylic acid

Guidance literature:

With potassium permanganate; In water; tert-butyl alcohol; for 16h; Reflux;

DOI:10.1021/acs.joc.9b01502

upstream raw materials:

1,2,3,4-Tetramethylbenzene

1,2-dichloro-3,4,5,6-tetrabromobenzene

dimethyl sulfate