RARECHEM AL BD 1228

Base Information

• Chemical Name: RARECHEM AL BD 1228
• CAS No.: 193602-41-4
• Molecular Formula: C5H5ClOS
• Molecular Weight: 148.61100
• Hs Code.: 2934999090
• Mol file: 193602-41-4.mol

Synonyms:3-CHLOROTHIOPHENE-2-METHANOL;3-CHLORO-2-(HYDROXYMETHYL)THIOPHENE;

Chemical Property of RARECHEM AL BD 1228

Chemical Property:

• Boiling Point: 239.7±25.0 °C(Predicted)
• PKA: 13.21±0.10(Predicted)
• PSA: 48.47000
• Density: 1.419±0.06 g/cm3(Predicted)
• LogP: 1.89380

Purity/Quality:

97% ^*data from raw suppliers

3-Chloro-2-(hydroxymethyl)thiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of RARECHEM AL BD 1228

There total 6 articles about RARECHEM AL BD 1228 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-chlorothiophene-2-carboxylic acid (59337-89-2) → (3-chlorothiophen-2-yl)methanol (193602-41-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.5b02256

Reference yield: 88.0%

3-chlorothiophene-2-carboxaldehyde (67482-48-8) → (3-chlorothiophen-2-yl)methanol (193602-41-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 35 ℃; for 16h;

Reference yield: 73.0%

→ (3-chlorothiophen-2-yl)methanol (193602-41-4)

Guidance literature:

upstream raw materials:

3-chlorothiophene-2-carboxylic acid

2-acetyl-3-chlorothiophene

ethyl 3-chlorothiophene-2-carboxylate

3-chlorothiophene-2-carboxaldehyde

Downstream raw materials:

2-(3-chlorothiophen-2-yl)acetonitrile