Pyridine, 2,6-bis(2-methoxyphenyl)-

Base Information

• Chemical Name: Pyridine, 2,6-bis(2-methoxyphenyl)-
• CAS No.: 195813-55-9
• Molecular Formula: C19H17NO2
• Molecular Weight: 291.349
• Mol file: 195813-55-9.mol

Synonyms:2,6-di(2-methoxyphenyl)pyridine;2,6-bis-(2'-methoxyphenyl)pyridine;Pyridine,2,6-bis(2-methoxyphenyl);

Chemical Property of Pyridine, 2,6-bis(2-methoxyphenyl)-

Chemical Property:

• PSA: 31.35000
• LogP: 4.43280

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyridine, 2,6-bis(2-methoxyphenyl)-

There total 14 articles about Pyridine, 2,6-bis(2-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,6-Dibromopyridine (626-05-1) + 2-Methoxyphenylboronic acid (5720-06-9) → 2,6-bis-(2'-methoxyphenyl)pyridine (195813-55-9)

Guidance literature:

With sodium phosphate dodecahydrate; palladium diacetate; In water; isopropyl alcohol; at 80 ℃; for 2h;

DOI:10.1021/ic400186x

Reference yield: 89.0%

2,6-Dibromopyridine (626-05-1) + potassium (2-methoxyphenyl)trifluoroborate → 2,6-bis-(2'-methoxyphenyl)pyridine (195813-55-9)

Guidance literature:

With {2,6-bis[(di-1-piperidinylphosphino)amino]phenyl}palladium(II) chloride; potassium carbonate; In 1,4-dioxane; water; butan-1-ol; at 100 ℃; for 3h;

DOI:10.1002/adsc.200900848

Reference yield: 85.0%

2,6-dichloropyridine (2402-78-0) + 2-Methoxyphenylboronic acid (5720-06-9) → 2,6-bis-(2'-methoxyphenyl)pyridine (195813-55-9)

Guidance literature:

With 4-di-tert-butylphosphanyl-1-phenyl-5-(2,6-dimethoxyphenyl)-1H-[1,2,3]triazole; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In toluene; at 100 ℃; for 12h; Inert atmosphere;

DOI:10.1055/s-0029-1216942

upstream raw materials:

2-Methoxyacetophenone

(2E)-3-(dimethylamino)-1-(2-methoxyphenyl)-2-propen-1-one

2,6-Dibromopyridine

2-bromoanisole

Downstream raw materials:

cis-2,6-bis(2-methoxyphenyl)piperidine

2,6-bis-(2'-hydroxyphenyl)pyridine