2-Aziridinecarboxylic acid, 1-(phenylmethyl)-, hydrazide

Base Information

• Chemical Name: 2-Aziridinecarboxylic acid, 1-(phenylmethyl)-, hydrazide
• CAS No.: 19615-19-1
• Molecular Formula: C₁₀H₁₃N₃O
• Molecular Weight: 191.233
• Mol file: 19615-19-1.mol

Synonyms:

Chemical Property of 2-Aziridinecarboxylic acid, 1-(phenylmethyl)-, hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Aziridinecarboxylic acid, 1-(phenylmethyl)-, hydrazide

There total 1 articles about 2-Aziridinecarboxylic acid, 1-(phenylmethyl)-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-benzyl-aziridine-2-carboxylic acid hydrazide (19615-19-1)

Guidance literature:

1-Benzyl-2-methoxycarbonyl-aziridin, Hydrazinhydrat;

DOI:10.1021/ja01015a069

Reference yield:

1-benzyl-aziridine-2-carboxylic acid hydrazide (19615-19-1) → 1-benzylaziridine-2-carboxylic acid azide (77119-28-9)

Guidance literature:

With nitrosylchloride; triethylamine; In 1,4-dioxane; diethyl ether; at -20 ℃; for 0.416667h;

DOI:10.1007/BF00496601

Reference yield:

1-benzyl-aziridine-2-carboxylic acid hydrazide (19615-19-1) → 2-[(1-Benzyl-aziridine-2-carbonyl)-amino]-succinic acid dimethyl ester (77119-27-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NOCl/Et₃N / diethyl ether; dioxane / 0.42 h / -20 °C

2: 15 percent / diethyl ether / 12 h / 0 °C

With nitrosylchloride; triethylamine; In 1,4-dioxane; diethyl ether;

DOI:10.1007/BF00496601

Downstream raw materials:

1-benzylaziridine-2-carboxylic acid azide

1-benzyl-aziridine-2-carboxylic acid benzylamide

[(1-Benzyl-aziridine-2-carbonyl)-amino]-acetic acid methyl ester

2-[(1-Benzyl-aziridine-2-carbonyl)-amino]-propionic acid methyl ester