2',4'-Dihydroxy-3'-prenylacetophenone

Base Information

• Chemical Name: 2',4'-Dihydroxy-3'-prenylacetophenone
• CAS No.: 19825-40-2
• Molecular Formula: C13H16O3
• Molecular Weight: 220.268
• DSSTox Substance ID: DTXSID30448850
• Nikkaji Number: J459.213A
• ChEMBL ID: CHEMBL1866176
• Mol file: 19825-40-2.mol

Synonyms:2',4'-dihydroxy-3'-prenylacetophenone;19825-40-2;1-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]ethanone;1-[2,4-dihydroxy-3-(3-methyl-2-butenyl)phenyl]ethanone;2-Prenyl-4-acetylresorcinol;MLS000697723;SCHEMBL5513553;CHEMBL1866176;DTXSID30448850;HUEWXRMYZUGMME-UHFFFAOYSA-N;HMS2270K13;3-prenyl-2,4-dihydroxyacetophenone;SMR000470988;AK-087/40841622;2',4'-dihydroxy-3'-(3-methyl-2-butenyl)acetophenone;1-[2,4-dihydroxy-3-(3-methyl-but-2-enyl)-phenyl]-ethanone

Chemical Property of 2',4'-Dihydroxy-3'-prenylacetophenone

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 220.109944368
• Heavy Atom Count: 16
• Complexity: 279

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=CCC1=C(C=CC(=C1O)C(=O)C)O)C

Technology Process of 2',4'-Dihydroxy-3'-prenylacetophenone

There total 21 articles about 2',4'-Dihydroxy-3'-prenylacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.1%

→ 2,4-Dihydroxy-3-C-prenylacetophenone (19825-40-2) + 4-benzyloxy-3-prenylresacetophenone (76609-42-2)

Guidance literature:

Reference yield: 60.0%

2',4'-dihydroxy-4-acetophenone (89-84-9) + isoprene (78-79-5,9003-31-0) → 2,4-Dihydroxy-3-C-prenylacetophenone (19825-40-2)

Guidance literature:

With chloro-trimethyl-silane; sodium iodide; In acetonitrile; for 18h; Ambient temperature;

DOI:10.1016/S0040-4039(01)81632-4

Reference yield: 59.0%

6-acetyl-2,2-dimethyl-3-phenylthiochroman-5-ol (87963-55-1) → 2,4-Dihydroxy-3-C-prenylacetophenone (19825-40-2)

Guidance literature:

With potassium naphthalenide; In tetrahydrofuran; for 1.33333h; Ambient temperature;

upstream raw materials:

2',3',4'-trihydroxyacetophenone

prenyl bromide

6-acetyl-2,2-dimethyl-3-phenylthiochroman-5-ol

6-acetyl-3-phenylsulphonyl-2,2-dimethylchroman-5-ol

Downstream raw materials:

4-Acetoxy-2-hydroxy-3-C-prenylresacetophenone

1-(2-hydroxy-4-methoxy-3-(3-methyl-butyl-2-ene-1-yl)phenyl)ethanone

2,4-Dimethoxy-3-C-prenylacetophenone

2',4'-dihydroxy-2,4-dimethoxy-3'-(3-methylbut-2-enyl)chalcone