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Technology Process of LY 334370 hydrochloride

LY 334370 hydrochloride

Base Information
  • Chemical Name:LY 334370 hydrochloride
  • CAS No.:199673-74-0
  • Molecular Formula:C21H22FN3O.ClH
  • Molecular Weight:387.87800
  • Hs Code.:
  • European Community (EC) Number:695-535-5
  • Mol file:199673-74-0.mol
LY 334370 hydrochloride

Synonyms:LY 334370 hydrochloride;199673-74-0;LY334370 (hydrochloride);4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide hydrochloride;4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamidehydrochloride;BenzaMide, 4-fluoro-N-[3-(1-Methyl-4-piperidinyl)-1H-indol-5-yl]-, Monohydrochloride;SCHEMBL8604274;LY 334370 HCl;ZHA67374;AKOS024457414;HY-103107A;4-FLUORO-N-(3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-YL)BENAZMIDE HYDROCHLORIDE;DS-017172;CS-0024339;E98851;J-011681;LY-334370 hydrochloride hydrate, >=98% (HPLC), powder;4-fluoro-n-(3-(1-methyl-4-piperidinyl)-1h-indol-5-yl)benzamide hcl;4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benzamide hydrochloride;4-fluoro-N-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]benzamide;hydrochloride;Benzamide, 4-fluoro-n-[3-(1-methyl-4-piperidinyl)-1h-indol-5-yl]-,monohydrochloride

Suppliers and Price of LY 334370 hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • LY334370Hydrochloride
  • 5mg
  • $ 415.00
  • Cayman Chemical
  • LY334370 (hydrochloride)
  • 10mg
  • $ 195.00
  • Cayman Chemical
  • LY334370 (hydrochloride)
  • 5mg
  • $ 146.00
  • Cayman Chemical
  • LY334370 (hydrochloride)
  • 1mg
  • $ 39.00
  • ApexBio Technology
  • LY334370hydrochloride
  • 50mg
  • $ 1385.00
  • ApexBio Technology
  • LY334370hydrochloride
  • 10mg
  • $ 339.00
  • AK Scientific
  • LY334370hydrochloride
  • 10mg
  • $ 363.00
Total 3 raw suppliers
Chemical Property of LY 334370 hydrochloride
Chemical Property:
  • PSA：48.13000 
  • LogP:5.18140 
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:3
  • Exact Mass:387.1513682
  • Heavy Atom Count:27
  • Complexity:486
Purity/Quality:

≥99% by HPLC *data from raw suppliers

LY334370Hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CN1CCC(CC1)C2=CNC3=C2C=C(C=C3)NC(=O)C4=CC=C(C=C4)F.Cl
  • Description LY334370 is an agonist of the serotonin (5-HT) receptor subtype 5-HT1F (Kd = 0.446 nM). It is selective for 5-HT1F over other G protein-coupled 5-HT receptor subtypes with Ki values ranging from 16.4 to greater than 3,000 nM in radioligand binding assays. LY334370 inhibits forskolin-induced cAMP accumulation in mouse L-M(TK-) cell membranes expressing the recombinant human 5-HT1F receptor (EC50 = 1.51 nM). It decreases electrically stimulated extravasation of plasma proteins in the dura mater in a guinea pig trigeminal nerve model of migraine headache.
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