1,2-DIPHYTANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Base Information

• Chemical Name: 1,2-DIPHYTANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
• CAS No.: 201036-16-0
• Molecular Formula: C45H90NO8P
• Molecular Weight: 804.17200
• Mol file: 201036-16-0.mol

Synonyms:

Chemical Property of 1,2-DIPHYTANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Chemical Property:

• Boiling Point: 774.3±70.0 °C(Predicted)
• PKA: 1.17±0.50(Predicted)
• PSA: 144.19000
• Density: 0.980±0.06 g/cm3(Predicted)
• LogP: 13.16460

Purity/Quality:

99% ^*data from raw suppliers

1,2-Diphytanoyl-sn-glycero-3-PE ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,2-DIPHYTANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE is phospholipids found in biological membranes that serve both structural and functional roles. Different types of PE are commonly used in the generation of micelles, liposomes, and other types of artificial membranes. 1,2-Diphytanoyl-sn-glycero-3-PE is a phospholipid containing the tetramethylated long-chain (16:0) diphytanic acid inserted at the sn-1 and sn-2 positions.[Cayman Chemical]

Technology Process of 1,2-DIPHYTANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

There total 3 articles about 1,2-DIPHYTANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,7,11,15-tetramethyl-1-hexadecanoyl chloride (32607-05-9) → 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine (29019-22-5,201036-16-0)

Guidance literature:

Multi-step reaction with 3 steps

1: Py / CHCl₃

2: Zn / aq. acetic acid; diethyl ether

3: (i) Py, CHCl₃, (ii) Zn, AcOH, Et₂O

With pyridine; zinc; In diethyl ether; chloroform; acetic acid;

DOI:10.1021/jm00288a008

Reference yield:

1,2-Dihydrophythyl-sn-glycerin-3-<(β,β,β-trichlorethyl)-carbonat> (32483-63-9) → 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine (29019-22-5,201036-16-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Zn / aq. acetic acid; diethyl ether

2: (i) Py, CHCl₃, (ii) Zn, AcOH, Et₂O

With zinc; In diethyl ether; acetic acid;

DOI:10.1021/jm00288a008

Reference yield:

1,2-Dihydrophythyl-sn-glycerin (32448-31-0,121785-39-5) + dichloro-<-2-amino>ethyl>phosphinic acid (32159-15-2) → 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine (29019-22-5,201036-16-0)

Guidance literature:

Multistep reaction; (i) Py, CHCl₃, (ii) Zn, AcOH, Et₂O;

DOI:10.1021/jm00288a008

upstream raw materials:

1,2-Dihydrophythyl-sn-glycerin

dichloro-<-2-amino>ethyl>phosphinic acid

3,7,11,15-tetramethyl-1-hexadecanoyl chloride

1,2-Dihydrophythyl-sn-glycerin-3-<(β,β,β-trichlorethyl)-carbonat>

Refernces