2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID

Base Information

• Chemical Name: 2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID
• CAS No.: 20146-24-1
• Molecular Formula: C15H11NO3
• Molecular Weight: 253.257
• Mol file: 20146-24-1.mol

Synonyms:2-[2]furyl-6-methyl-quinoline-4-carboxylic acid;2-[2]Furyl-6-methyl-chinolin-4-carbonsaeure;2-furan-2-yl-6-methyl-quinoline-4-carboxylic acid;6-Methyl-2--cinchoninsaeure;

Chemical Property of 2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID

Chemical Property:

• Melting Point: 250 °C
• PSA: 63.33000
• LogP: 3.50140

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-Furyl)-6-methylquinoline-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID

There total 4 articles about 2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

1-(2-furyl)-1-ethanone (1192-62-7,80145-44-4) + 5-methyl-indole-2,3-dione (608-05-9) → 2-(2-furyl)-6-methyl-4-quinolinecarboxylic acid (20146-24-1)

Guidance literature:

With sodium hydroxide; for 2h; Heating;

Reference yield: 47.0%

furfural (98-01-1) + p-toluidine (106-49-0,12221-03-3) + 2-oxo-propionic acid (127-17-3) → 2-(2-furyl)-6-methyl-4-quinolinecarboxylic acid (20146-24-1)

Guidance literature:

With triethylamine; In ethanol; at 20 - 80 ℃;

Reference yield:

furfural (98-01-1) + p-toluidine (106-49-0,12221-03-3) + 2-oxo-propionic acid (127-17-3) → 2-(2-furyl)-6-methyl-4-quinolinecarboxylic acid (20146-24-1)

Guidance literature:

With ethanol;

upstream raw materials:

furfural

p-toluidine

2-oxo-propionic acid

1-(2-furyl)-1-ethanone

Downstream raw materials:

C₂₁H₂₃N₃O₂

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