Ethyl (3R,4R,5S)-4-Amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Base Information

Chemical Name:Ethyl (3R,4R,5S)-4-Amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate
CAS No.:204255-04-9
Molecular Formula:C14H24N4O3
Molecular Weight:296.37
Hs Code.:
European Community (EC) Number:805-634-9
Mol file:204255-04-9.mol

Synonyms:Ethyl (3R,4R,5S)-4-Amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate;ethyl (3R,4R,5S)-4-amino-5-azido-3-pentan-3-yloxycyclohexene-1-carboxylate;204255-04-9;SCHEMBL13448860;UXJWNTIKRKKBGZ-YNEHKIRRSA-N;(3R,4R,5S)-4-amino-5-azido-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester

Suppliers and Price of Ethyl (3R,4R,5S)-4-Amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Desacetyl5-AzidoOseltamivir
100mg
$ 1110.00

TRC
N-Desacetyl5-AzidoOseltamivir
10mg
$ 140.00

TRC
N-Desacetyl5-AzidoOseltamivir
5mg
$ 100.00

Biosynth Carbosynth
N-Desacetyl 5-azido oseltamivir
100 mg
$ 1529.00

Biosynth Carbosynth
N-Desacetyl 5-azido oseltamivir
50 mg
$ 841.50

Biosynth Carbosynth
N-Desacetyl 5-azido oseltamivir
25 mg
$ 463.00

Biosynth Carbosynth
N-Desacetyl 5-azido oseltamivir
10 mg
$ 254.50

Biosynth Carbosynth
N-Desacetyl 5-azido oseltamivir
5 mg
$ 140.00

Total 14 raw suppliers

Chemical Property of Ethyl (3R,4R,5S)-4-Amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Chemical Property:

PSA：111.30000
LogP:2.61266
Storage Temp.:-20?C Freezer
Solubility.:Chloroform, Ethyl Acetate
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:296.18484064
Heavy Atom Count:21
Complexity:428

Purity/Quality:

99%, ^*data from raw suppliers

N-Desacetyl5-AzidoOseltamivir ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CC)OC1C=C(CC(C1N)N=[N+]=[N-])C(=O)OCC
Isomeric SMILES:CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1N)N=[N+]=[N-])C(=O)OCC
Uses Intermediate in the production of Oseltamivir. It is a COVID19-related research product.

Technology Process of Ethyl (3R,4R,5S)-4-Amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

There total 22 articles about Ethyl (3R,4R,5S)-4-Amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 204255-02-7
ethyl-(1R,5R,6R)-5-(pentan-3-yloxy)-7-azabicyclo[4.1.0]hept-3-ene-3-carboxylate

: 204255-04-9
ethyl-(3R,4R,5S)-4-amino-5-azido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate

Guidance literature:: With sodium azide; ammonium chloride; In N,N-dimethyl-formamide; at 65 - 70 ℃; for 16h;
DOI:10.14233/ajchem.2018.21376

Reference yield:

: 1132660-00-4
(3R,4R,5S)-5-azido-4-(diethoxy-phosphorylamino)-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester

: 204255-04-9
ethyl-(3R,4R,5S)-4-amino-5-azido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate

Guidance literature:: (3R,4R,5S)-5-azido-4-(diethoxy-phosphorylamino)-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester; With sulfuric acid; In ethanol; at 20 - 80 ℃; for 26h;

With ammonia; In ethanol; water;