4-[2-(1H-imidazol-1-yl)ethoxy]benzaldehyde

Base Information

Chemical Name:4-[2-(1H-imidazol-1-yl)ethoxy]benzaldehyde
CAS No.:205371-43-3
Molecular Formula:C₁₂H₁₂N₂O₂
Molecular Weight:216.239
Hs Code.:2933290090
DSSTox Substance ID:DTXSID10441420
Nikkaji Number:J3.472.604C
Wikidata:Q82258182
Mol file:205371-43-3.mol

Synonyms:205371-43-3;4-[2-(1H-imidazol-1-yl)ethoxy]benzaldehyde;4-(2-imidazol-1-ylethoxy)benzaldehyde;4-(2-(1H-Imidazol-1-yl)ethoxy)benzaldehyde;Benzaldehyde, 4-[2-(1H-imidazol-1-yl)ethoxy]-;SCHEMBL4131855;DTXSID10441420;QCVBRBJRYISOFD-UHFFFAOYSA-N;4-[2-(1H-Imidazole-1-yl)ethoxy]benzaldehyde;EN300-10163471

Suppliers and Price of 4-[2-(1H-imidazol-1-yl)ethoxy]benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-[2-(1H-IMIDAZOL-1-YL)ETHOXY]BENZALDEHYDE 95.00%
5MG
$ 505.82

Total 2 raw suppliers

Chemical Property of 4-[2-(1H-imidazol-1-yl)ethoxy]benzaldehyde

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:458.528oC at 760 mmHg
Flash Point:231.11oC
PSA：44.12000
Density:1.15g/cm3
LogP:1.77460
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:216.089877630
Heavy Atom Count:16
Complexity:215

Purity/Quality:: 4-[2-(1H-IMIDAZOL-1-YL)ETHOXY]BENZALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=O)OCCN2C=CN=C2

Technology Process of 4-[2-(1H-imidazol-1-yl)ethoxy]benzaldehyde

There total 3 articles about 4-[2-(1H-imidazol-1-yl)ethoxy]benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 288-32-4
1H-imidazole

: 52191-15-8
4-(2-bromoethyloxy)benzaldehyde

: 205371-43-3
4-[2-(1H-imidazole-1-yl)ethoxy]benzaldehyde

Guidance literature:: 1H-imidazole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

4-(2-bromoethyloxy)benzaldehyde; In N,N-dimethyl-formamide; at 25 ℃; for 20h;
DOI:10.1246/cl.160107

Reference yield:

: 288-32-4
1H-imidazole

: 54373-15-8
4-(2-chloroethoxy)benzaldehyde

: 205371-43-3
4-[2-(1H-imidazole-1-yl)ethoxy]benzaldehyde

Guidance literature:: 4-(2-chloroethoxy)benzaldehyde; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

1H-imidazole; In N,N-dimethyl-formamide; at 20 - 60 ℃; for 22.5h;

Reference yield:

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 205371-43-3
4-[2-(1H-imidazole-1-yl)ethoxy]benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 80 °C

2: potassium carbonate / N,N-dimethyl-formamide / 6 h / 80 °C

With potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.11.004