3,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzaldehyde

Base Information

• Chemical Name: 3,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzaldehyde
• CAS No.: 206049-38-9
• Molecular Formula: C21H34O9
• Molecular Weight: 430.496
• DSSTox Substance ID: DTXSID40477813
• Nikkaji Number: J3.150.176H
• Wikidata: Q82310736
• Mol file: 206049-38-9.mol

Synonyms:206049-38-9;3,5-bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzaldehyde;SCHEMBL6002467;DTXSID40477813;JWFKZRZVFDEUIG-UHFFFAOYSA-N;Benzaldehyde, 3,5-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-;3,5-bis(9-methoxy-1,4,7-trioxanonyl)benzaldehyde

Chemical Property of 3,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzaldehyde

Chemical Property:

• XLogP3: 0
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 21
• Exact Mass: 430.22028266
• Heavy Atom Count: 30
• Complexity: 354

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCOCCOCCOC1=CC(=CC(=C1)C=O)OCCOCCOCCOC

Technology Process of 3,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzaldehyde

There total 9 articles about 3,5-Bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(3,5-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenyl)-methanol (206049-37-8) → 3,5-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-benzaldehyde (206049-38-9)

Guidance literature:

(3,5-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenyl)-methanol; With pyridinium chlorochromate; In dichloromethane; at 10 ℃; for 4h;

In diethyl ether; dichloromethane; for 1h;

DOI:10.1080/10610278.2015.1092535

Reference yield: 71.0%

3,5-dihydroxybenzaldehyde (26153-38-8) + 2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate (62921-74-8,518012-62-9,58320-73-3) → 3,5-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-benzaldehyde (206049-38-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 1h; Heating;

DOI:10.1021/ja0203925

Reference yield: 59.2%

triethylene glucol monomethyl ether (112-35-6,95507-80-5) + 3,5-dibromobenzaldehyde (56990-02-4) → 3,5-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-benzaldehyde (206049-38-9)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1021/ma0506233

upstream raw materials:

(3,5-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenyl)-methanol

3,5-dihydroxybenzaldehyde

2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate

triethylene glucol monomethyl ether

Downstream raw materials:

5,10-bis{3,5-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl}tripyrrane

C₂₂H₃₆O₈