(2-Azidophenyl)methanol

Base Information

• Chemical Name: (2-Azidophenyl)methanol
• CAS No.: 20615-76-3
• Molecular Formula: C7H7N3O
• Molecular Weight: 149.152
• DSSTox Substance ID: DTXSID701314558
• Nikkaji Number: J2.452.746H
• Mol file: 20615-76-3.mol

Synonyms:(2-azidophenyl)methanol;2-Azidobenzyl alcohol;20615-76-3;2-azidophenylmethanol;2-Azidobenzenemethanol;SCHEMBL18138363;XRMVEVLFARNQHG-UHFFFAOYSA-N;DTXSID701314558;EN300-187980

Chemical Property of (2-Azidophenyl)methanol

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 149.058911855
• Heavy Atom Count: 11
• Complexity: 165

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CO)N=[N+]=[N-]

Technology Process of (2-Azidophenyl)methanol

There total 10 articles about (2-Azidophenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Aminobenzyl alcohol (5344-90-1) → 2-azidobenzyl alcohol (20615-76-3)

Guidance literature:

2-Aminobenzyl alcohol; With hydrogenchloride; sodium nitrite; In water; at -5 - -3 ℃; for 0.0833333h;

With sodium azide; sodium acetate; In water; at 0 ℃; for 2h; Further stages.;

DOI:10.1021/ol010220x

Reference yield: 89.0%

2-azidobenzaldehyde (16714-25-3) → 2-azidobenzyl alcohol (20615-76-3)

Guidance literature:

With sodium tetrahydroborate; In methanol; dichloromethane; at 0 - 20 ℃; for 0.75h; Inert atmosphere;

DOI:10.1039/d0cc05031h

Reference yield:

2-(hydroxymethyl)phenylboronic acid (87199-14-2) → 2-azidobenzyl alcohol (20615-76-3)

Guidance literature:

With sodium azide; copper diacetate; In water; acetonitrile; at 20 ℃;

DOI:10.1016/j.ejmech.2016.05.018

upstream raw materials:

2-Aminobenzyl alcohol

1-azido-2-methyl-benzene

anthranilic acid

o-Hydroxymethyl-benzoldiazonium

Downstream raw materials:

2-phenyl-1,4-dihydro-2H-2λ⁵-spiro[benzo[d][1,3,2]oxazaphosphinine-2,2'-[1,3,2]dioxaphospholane]

2-azidobenzaldehyde

2-<(Triphenylphosphoranylidene)amino>benzyl Alcohol

Bis(2,2'-diazidobenzyl) ether