1-[3-CYANO-4-(2,2-DIMETHYL-PROPOXY)-PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID

Base Information

Chemical Name:1-[3-CYANO-4-(2,2-DIMETHYL-PROPOXY)-PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID
CAS No.:206884-98-2
Molecular Formula:C16H17N3O3
Molecular Weight:299.32400
Hs Code.:
Mol file:206884-98-2.mol

Synonyms:Y-700;UNII-246FR6022S;Piraxostat;niraxostat;YSH;

Suppliers and Price of 1-[3-CYANO-4-(2,2-DIMETHYL-PROPOXY)-PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Axon Medchem
Y 700 - Piraxostat 99%
25 mg
$ 594.00

Axon Medchem
Y 700 - Piraxostat 99%
5 mg
$ 148.00

American Custom Chemicals Corporation
PIRAXOSTAT 95.00%
25MG
$ 1390.75

American Custom Chemicals Corporation
PIRAXOSTAT 95.00%
5MG
$ 320.10

Total 7 raw suppliers

Chemical Property of 1-[3-CYANO-4-(2,2-DIMETHYL-PROPOXY)-PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID

Chemical Property:

PSA：88.14000
LogP:2.86708

Purity/Quality:

98%min ^*data from raw suppliers

Y 700 - Piraxostat 99% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[3-CYANO-4-(2,2-DIMETHYL-PROPOXY)-PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID

There total 6 articles about 1-[3-CYANO-4-(2,2-DIMETHYL-PROPOXY)-PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 206884-97-1
ethyl 1-(3'-cyano-4'-neopentyloxyphenyl)-pyrazol-4-carboxylate

: 206884-98-2
[14C]-Piraxostat

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; ethanol; at 60 ℃; for 2h;
DOI:10.1016/j.ejmech.2017.08.047

Reference yield:

: 206885-30-5
3-cyano-4-neopentyloxy-phenylhydrazine

: 206884-98-2
[14C]-Piraxostat

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / Heating

2: isoamyl nitrite / tetrahydrofuran

3: 1 N aq. NaOH / ethanol

With sodium hydroxide; isopentyl nitrite; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(01)00093-2

Reference yield:

: 3-amino-1-[3-cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyrazole-4-carboxylic acid ethyl ester

: 206884-98-2
[14C]-Piraxostat

Guidance literature:: Multi-step reaction with 2 steps

1: isoamyl nitrite / tetrahydrofuran

2: 1 N aq. NaOH / ethanol

With sodium hydroxide; isopentyl nitrite; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(01)00093-2