5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione

Base Information Edit

Chemical Name:5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione
CAS No.:18274-81-2
Molecular Formula:C9H6OS3
Molecular Weight:226.344
Hs Code.:2930909090
UNII:P3SE9K2LHV
DSSTox Substance ID:DTXSID40939623,DTXSID00901548
Nikkaji Number:J1.015.095G
Wikidata:Q82916162
ChEMBL ID:CHEMBL402341
Mol file:18274-81-2.mol

Synonyms:desmethyl-ADT;desmethylanethol dithiolthione;desmethylanethol trithione

Suppliers and Price of 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Desmethylanetholtrithione 97%
1g
$ 400.00

Matrix Scientific
Desmethylanetholtrithione 97%
5g
$ 1200.00

DC Chemicals
ADT-OH >98%
100 mg
$ 500.00

Crysdot
5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione 97%
10g
$ 950.00

Crysdot
5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione 97%
5g
$ 594.00

Chemenu
5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione 95+%
25g
$ 1702.00

Chemenu
5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione 95+%
5g
$ 561.00

Chemenu
5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione 95+%
10g
$ 898.00

Chemenu
5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione 95+%
1g
$ 204.00

Cayman Chemical
ADT-OH ≥98%
10mg
$ 45.00

Total 18 raw suppliers

Chemical Property of 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione Edit

Chemical Property:

Vapor Pressure:0.000284mmHg at 25°C
Melting Point:191-192 °C
Boiling Point:322.2°Cat760mmHg
PKA:9.78±0.30(Predicted)
Flash Point:148.6°C
PSA：106.47000
Density:1.48g/cm³
LogP:3.10180
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:225.95807833
Heavy Atom Count:13
Complexity:241

Purity/Quality:

99% ^*data from raw suppliers

Desmethylanetholtrithione 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC(=S)SS2)O
Description ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. It can be readily esterified with other moieties. For example, it can be coupled with therapeutics like nonsteroidal anti-inflammatory drugs, as in the generation of ATB-343 . ADT-OH has also been linked with a mitochondria-targeting motif to produce AP-39 , which selectively increases mitochondrial H2S levels. ADT-OH is used both in cells and in animals for comparative studies with derived chimeras.
Uses is used in method for preventing or treating diseases associated with administration of VEGFR and/or VEGF inhibitor.

Technology Process of 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione

There total 12 articles about 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%