Chemical Property of 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione
Chemical Property:
- Vapor Pressure:0.000284mmHg at 25°C
- Melting Point:191-192 °C
- Boiling Point:322.2°Cat760mmHg
- PKA:9.78±0.30(Predicted)
- Flash Point:148.6°C
- PSA：106.47000
- Density:1.48g/cm3
- LogP:3.10180
- Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
- XLogP3:2.4
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:1
- Exact Mass:225.95807833
- Heavy Atom Count:13
- Complexity:241
- Purity/Quality:
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97% *data from raw suppliers
Desmethylanetholtrithione 97% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC(=CC=C1C2=CC(=S)SS2)O
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Description
ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. It can be readily esterified with other moieties. For example, it can be coupled with therapeutics like nonsteroidal anti-inflammatory drugs, as in the generation of ATB-343 . ADT-OH has also been linked with a mitochondria-targeting motif to produce AP-39 , which selectively increases mitochondrial H2S levels. ADT-OH is used both in cells and in animals for comparative studies with derived chimeras.
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Uses
is used in method for preventing or treating diseases associated with administration of VEGFR and/or VEGF inhibitor.
