2,3,5-Triphenylthiophene

Base Information

• Chemical Name: 2,3,5-Triphenylthiophene
• CAS No.: 20851-07-4
• Molecular Formula: C22H16S
• Molecular Weight: 312.435
• DSSTox Substance ID: DTXSID80462081
• Nikkaji Number: J1.288.222J
• Wikidata: Q82286560
• Mol file: 20851-07-4.mol

Synonyms:2,3,5-triphenylthiophene;Thiophene, 2,3,5-triphenyl-;20851-07-4;2,3,5-Triphenyl-thiophene;SCHEMBL9755135;DTXSID80462081

Chemical Property of 2,3,5-Triphenylthiophene

Chemical Property:

• XLogP3: 6.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 312.09727168
• Heavy Atom Count: 23
• Complexity: 347

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC(=C(S2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 2,3,5-Triphenylthiophene

There total 44 articles about 2,3,5-Triphenylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,4-diphenylthiophene (3328-86-7) + Diphenyliodonium triflate (66003-76-7) → 2,3,5-triphenylthiophene (20851-07-4)

Guidance literature:

With copper(I) triflate; In 1,2-dichloro-ethane; at 90 ℃; for 8h; Inert atmosphere; Schlenk technique;

DOI:10.1039/d1nj05433c

Reference yield: 90.0%

2-phenylthiophene (825-55-8) + bromobenzene (108-86-1,52753-63-6) → 2,5-Diphenyl-thiophene (1445-78-9) + 2,3,5-triphenylthiophene (20851-07-4)

Guidance literature:

With palladium diacetate; P(O-biphenyl)(t-Bu)2; caesium carbonate; In o-xylene; for 24h; Heating;

DOI:10.1021/ja0259279

Reference yield: 88.0%

bromobenzene (108-86-1,52753-63-6) + 3-phenylthiophene (2404-87-7) → 2,3,5-triphenylthiophene (20851-07-4)

Guidance literature:

With palladium diacetate; P(O-biphenyl)(t-Bu)2; caesium carbonate; In o-xylene; for 24h; Heating;

DOI:10.1021/ja0259279

upstream raw materials:

(Z)-1,2,4-triphenyl-2-butene-1,4-dione

1,2,4-triphenylbutane-1,4-dione

Lawessons reagent

benzalacetophenone