4(3H)-Quinazolinone, 2-[(acetyloxy)methyl]-3-phenyl-

Base Information

Chemical Name:4(3H)-Quinazolinone, 2-[(acetyloxy)methyl]-3-phenyl-
CAS No.:20873-19-2
Molecular Formula:C17H14N2O3
Molecular Weight:294.31
Hs Code.:
DSSTox Substance ID:DTXSID30465562
Wikidata:Q82291607

Synonyms:20873-19-2;(4-Oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)methyl acetate;4(3H)-Quinazolinone, 2-[(acetyloxy)methyl]-3-phenyl-;DTXSID30465562

Suppliers and Price of 4(3H)-Quinazolinone, 2-[(acetyloxy)methyl]-3-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4(3H)-Quinazolinone, 2-[(acetyloxy)methyl]-3-phenyl-

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:294.10044231
Heavy Atom Count:22
Complexity:469

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCC1=NC2=CC=CC=C2C(=O)N1C3=CC=CC=C3

Technology Process of 4(3H)-Quinazolinone, 2-[(acetyloxy)methyl]-3-phenyl-

There total 3 articles about 4(3H)-Quinazolinone, 2-[(acetyloxy)methyl]-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 62-53-3
aniline

: 51815-70-4
N-(acetocyacetyl)anthranilic acid

: 20873-19-2
2-acetoxymethyl-3-phenyl-4-oxo-3,4-dihydroquinazoline

Guidance literature:: With phosphorus trichloride; In acetonitrile; at 50 ℃; for 2h;
DOI:10.1021/jo049118e

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 20873-19-2
2-acetoxymethyl-3-phenyl-4-oxo-3,4-dihydroquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 1 h / 20 °C

2: 96 percent / PCl₃ / acetonitrile / 2 h / 50 °C

With triethylamine; phosphorus trichloride; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jo049118e