N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxycarbonyl)aminomethyl]benzamide

Base Information

Chemical Name:N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxycarbonyl)aminomethyl]benzamide
CAS No.:209783-81-3
Molecular Formula:C22H21N3O3
Molecular Weight:375.427
Hs Code.:
DSSTox Substance ID:DTXSID001145786
ChEMBL ID:CHEMBL357268

Synonyms:CHEMBL357268;N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxycarbonyl)aminomethyl]benzamide;HDInhib_000007;SCHEMBL2410629;DTXSID001145786;BDBM50474342;benzyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate;Phenylmethyl N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate;209783-81-3

Suppliers and Price of N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxycarbonyl)aminomethyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxycarbonyl)aminomethyl]benzamide

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:375.15829154
Heavy Atom Count:28
Complexity:499

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NCC2=CC=C(C=C2)C(=O)NC3=CC=CC=C3N

Technology Process of N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxycarbonyl)aminomethyl]benzamide

There total 4 articles about N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxycarbonyl)aminomethyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: 58933-52-1
4-((benzyloxycarbonylamino)methyl)benzoic acid

: 95-54-5
1,2-diamino-benzene

: 209783-81-3
benzyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate

Guidance literature:: 4-((benzyloxycarbonylamino)methyl)benzoic acid; With 4-methyl-morpholine; isobutyl chloroformate; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

1,2-diamino-benzene; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 56-91-7
p-aminomethylbenzoic acid

: 209783-81-3
benzyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / acetone; water / 0 - 20 °C

2.1: 4-methyl-morpholine; isobutyl chloroformate / N,N-dimethyl-formamide / 0.25 h / 20 °C

2.2: 20 °C

With 4-methyl-morpholine; sodium hydrogencarbonate; isobutyl chloroformate; In water; N,N-dimethyl-formamide; acetone;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 209783-81-3
benzyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / acetone; water / 0 - 20 °C

2.1: 4-methyl-morpholine; isobutyl chloroformate / N,N-dimethyl-formamide / 0.25 h / 20 °C

2.2: 20 °C

With 4-methyl-morpholine; sodium hydrogencarbonate; isobutyl chloroformate; In water; N,N-dimethyl-formamide; acetone;