1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)-

Base Information

Chemical Name:1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)-
CAS No.:88763-98-8
Molecular Formula:C₂₀H₂₃N
Molecular Weight:277.409
Hs Code.:
DSSTox Substance ID:DTXSID90237303
Wikidata:Q76422949

Synonyms:1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)-;88763-15-9;BRN 4695713;BRN 5752694;DTXSID90237303;1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-1-methyl-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)-;88763-98-8

Suppliers and Price of 1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)-

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:277.183049738
Heavy Atom Count:21
Complexity:365

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC=C1)C2C3CCCN(C3C4=CC=CC=C24)C
Isomeric SMILES:CC1=CC(=CC=C1)[C@H]2[C@H]3CCCN([C@H]3C4=CC=CC=C24)C

Technology Process of 1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)-

There total 5 articles about 1H-Indeno(1,2-b)pyridine, 2,3,4,4a,5,9b-hexahydro-5-(3-methylphenyl)-, (4a-alpha,5-beta,9b-alpha)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 81153-14-2
(4aR,5R,9bR)-1-Methyl-5-m-tolyl-1,3,4,4a,5,9b-hexahydro-indeno[1,2-b]pyridin-2-one

: 88763-98-8
(4aR,5R,9bR)-1-Methyl-5-m-tolyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 6h; Heating;

Reference yield:

: 10413-00-0
5-oxo-5-phenylpentanenitrile

: 88763-98-8
(4aR,5R,9bR)-1-Methyl-5-m-tolyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 45 percent / 85percentiger Phosphorsaeure, Phosphorpentoxid / 3 h / 80 °C

2: 78 percent / hydrogen / Raney-Nickel

3: 1.) Natriumamid / 1.) Toluol, zweienhalb Stunden, Rueckfluss, 2.) 4 Stunden, Rueckfluss

4: 85 percent / Lithiumaluminiumhydrid / diethyl ether / 6 h / Heating

With lithium aluminium tetrahydride; phosphoric acid; hydrogen; phosphorus pentoxide; sodium amide; nickel; In diethyl ether;

Reference yield:

: 81152-85-4
5-m-Tolyl-1,3,4,5-tetrahydro-indeno[1,2-b]pyridin-2-one

: 88763-98-8
(4aR,5R,9bR)-1-Methyl-5-m-tolyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / hydrogen / Raney-Nickel

2: 1.) Natriumamid / 1.) Toluol, zweienhalb Stunden, Rueckfluss, 2.) 4 Stunden, Rueckfluss

3: 85 percent / Lithiumaluminiumhydrid / diethyl ether / 6 h / Heating

With lithium aluminium tetrahydride; hydrogen; sodium amide; nickel; In diethyl ether;