L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, pentachlorophenyl ester

Base Information

• Chemical Name: L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, pentachlorophenyl ester
• CAS No.: 21148-96-9
• Molecular Formula: C20H18Cl5NO4
• Molecular Weight: 513.632
• Mol file: 21148-96-9.mol

Synonyms:

Chemical Property of L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, pentachlorophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, pentachlorophenyl ester

There total 2 articles about L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, pentachlorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Pentachlorophenol (87-86-5,67471-28-7) + N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) → N-(tert-butoxycarbonyl)-L-phenylalanine pentachlorophenyl ester (21148-96-9)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.1021/jo01276a048

Reference yield:

→ N-(tert-butoxycarbonyl)-L-phenylalanine pentachlorophenyl ester (21148-96-9)

Guidance literature:

Boc-Phe, CCl3-COOC6Cl5;

Reference yield: 80.0%

N-(tert-butoxycarbonyl)-L-phenylalanine pentachlorophenyl ester (21148-96-9) → (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol (66605-57-0)

Guidance literature:

With sodium tetrahydroborate; iodine; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/a902069a

upstream raw materials:

Pentachlorophenol

N-tert-butoxycarbonyl-L-phenylalanine

Downstream raw materials:

benzyl 2,3,4-tri-O-benzyl-1-O--D-glucopyranuronate

benzyl 2,3,4-tri-O-benzyl-1-O--D-glucopyranuronate

2,3,4,6-tetra-O-acetyl-1-O--β-D-glucopyranose

2,3,4,6-tetra-O-acetyl-1-O--α-D-glucopyranose