4-Oxazolecarboxylic acid, 5-[(1E)-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-propenyl]-4,5-dihydro- 4-methyl-2-phenyl-, methyl ester, (4S,5S)-

Base Information

Chemical Name:4-Oxazolecarboxylic acid, 5-[(1E)-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-propenyl]-4,5-dihydro- 4-methyl-2-phenyl-, methyl ester, (4S,5S)-
CAS No.:211691-17-7
Molecular Formula:C31H35NO4Si
Molecular Weight:513.709
Hs Code.:

4-Oxazolecarboxylic acid,
5-[(1E)-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-propenyl]-4,5-dihydro-
4-methyl-2-phenyl-, methyl ester, (4S,5S)-

Synonyms:

Suppliers and Price of 4-Oxazolecarboxylic acid, 5-[(1E)-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-propenyl]-4,5-dihydro- 4-methyl-2-phenyl-, methyl ester, (4S,5S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Oxazolecarboxylic acid, 5-[(1E)-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-propenyl]-4,5-dihydro- 4-methyl-2-phenyl-, methyl ester, (4S,5S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Oxazolecarboxylic acid, 5-[(1E)-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-propenyl]-4,5-dihydro- 4-methyl-2-phenyl-, methyl ester, (4S,5S)-

There total 3 articles about 4-Oxazolecarboxylic acid, 5-[(1E)-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-propenyl]-4,5-dihydro- 4-methyl-2-phenyl-, methyl ester, (4S,5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 389806-78-4
methyl (2S,3R,4E)-2-benzamido-2-methyl-3-hydroxy-6-(tert-butyldiphenylsilyloxy)-4-hexenoate

: 211691-17-7
(+)-(1'E,4S,5S)-5-[3'-t-butyldiphenylsilyloxy-prop-1'-enyl]-4-methyl-4-methoxycarbonyl-2-phenyl-4,5-dihydro-oxazole

Guidance literature:: With pyridine; methanesulfonyl chloride; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1021/ja0118338

Reference yield:

: 211691-13-3
methyl (2S,3R,4E)-3-acetoxy-2-benzamido-2-methyl-6-(tertbutyldiphenylsilyloxy)-4-hexenoate

: 211691-17-7
(+)-(1'E,4S,5S)-5-[3'-t-butyldiphenylsilyloxy-prop-1'-enyl]-4-methyl-4-methoxycarbonyl-2-phenyl-4,5-dihydro-oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 2.05 g / K₂CO₃ / methanol / 0.5 h / 0 °C

2: 99 percent / methansulfonyl chloride; pyridine / CH₂Cl₂ / 3 h / 20 °C

With pyridine; potassium carbonate; methanesulfonyl chloride; In methanol; dichloromethane;
DOI:10.1021/ja0118338

Reference yield:

: 211691-11-1
(1'R,4S,2'E)-4-[1'-acetoxy-4'-(tertbutyldiphenylsilyloxy)but-2'-en-1'-yl]-4-methyl-2-phenyl-4,5-dihydro-5-oxazolone

: 211691-17-7
(+)-(1'E,4S,5S)-5-[3'-t-butyldiphenylsilyloxy-prop-1'-enyl]-4-methyl-4-methoxycarbonyl-2-phenyl-4,5-dihydro-oxazole

Guidance literature:: Multi-step reaction with 3 steps

1: TsOH*H₂O / 8 h / 25 °C

2: 2.05 g / K₂CO₃ / methanol / 0.5 h / 0 °C

3: 99 percent / methansulfonyl chloride; pyridine / CH₂Cl₂ / 3 h / 20 °C

With pyridine; potassium carbonate; toluene-4-sulfonic acid; methanesulfonyl chloride; In methanol; dichloromethane;
DOI:10.1021/ja0118338