(2,3-Dihydrobenzofuran-2-yl)methanamine

Base Information

• Chemical Name: (2,3-Dihydrobenzofuran-2-yl)methanamine
• CAS No.: 21214-11-9
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.192
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID40274884
• Nikkaji Number: J2.987.624J
• Mol file: 21214-11-9.mol

Synonyms:(2,3-Dihydrobenzofuran-2-yl)methanamine;21214-11-9;2,3-dihydro-1-benzofuran-2-ylmethanamine;C-(2,3-Dihydro-benzofuran-2-yl)-methylamine;1-(2,3-dihydro-1-benzofuran-2-yl)methanamine;(2,3-dihydro-1-benzofuran-2-yl)methanamine;2-aminomethyl-2,3-dihydrobenzofuran;SCHEMBL718265;DTXSID40274884;ASPSZCAHOMXPBE-UHFFFAOYSA-N;HMS1681H19;MFCD03724810;STK503417;19997-54-7 (HCl salt);AKOS000169118;AKOS016042122;2-(Aminomethyl)-2,3-dihydrobenzofuran;SB35375;NCGC00343055-01;BS-13452;BB 0259356;FT-0767361;EN300-35758;c-(2,3-dihydrobenzo[b]furan-2-yl)methylamine;AB01334944-02;A879197;F8881-5515;Z291234246

Chemical Property of (2,3-Dihydrobenzofuran-2-yl)methanamine

Chemical Property:

• PSA: 35.25000
• LogP: 1.64910
• Storage Temp.: 2-8°C
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 149.084063974
• Heavy Atom Count: 11
• Complexity: 138

Purity/Quality:

97% ^*data from raw suppliers

(2,3-Dihydrobenzofuran-2-yl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C(OC2=CC=CC=C21)CN

Technology Process of (2,3-Dihydrobenzofuran-2-yl)methanamine

There total 7 articles about (2,3-Dihydrobenzofuran-2-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-(azidomethyl)-2,3-dihydrobenzofuran (1311989-93-1) → (2,3-dihydrobenzofuran-2-yl)methanamine (21214-11-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃;

DOI:10.1039/c1ob05116d

Reference yield: 62.0%

2,3-Dihydrobenzo[b]furan-2-carboxamide (57537-75-4) → (2,3-dihydrobenzofuran-2-yl)methanamine (21214-11-9)

Guidance literature:

2,3-Dihydrobenzo[b]furan-2-carboxamide; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 4h; Heating / reflux;

With water; In tetrahydrofuran; at 0 ℃;

Reference yield:

2-(iodomethyl)-2,3-dihydro-1-benzofuran (59152-49-7) → (2,3-dihydrobenzofuran-2-yl)methanamine (21214-11-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide; copper / N,N-dimethyl-formamide / 90 °C

2: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C

With sodium azide; palladium 10% on activated carbon; hydrogen; copper; In ethanol; N,N-dimethyl-formamide;

DOI:10.1039/c1ob05116d

upstream raw materials:

2,3-Dihydrobenzo[b]furan-2-carboxamide

2-(iodomethyl)-2,3-dihydro-1-benzofuran

2-(azidomethyl)-2,3-dihydrobenzofuran

allyl phenyl ether

Downstream raw materials:

3-(2-(4-bromophenyl)-2-oxoethyl)-1-((2,3-dihydrobenzofuran-2-yl)methyl)-1H-imidazol-3-ium bromide

1-((2,3-dihydrobenzofuran-2-yl)methyl)-3-(2-(4-methoxyphenyl)-2-oxoethyl)-1H-imidazol-3-ium bromide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 21214-11-9 3-dihydrobenzofuran-2-yl)MethanaMine

Send

Send

Metric Ton KG G Pound L ML

Send

Send