4-Methyl-N-[(1S,2S)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

Base Information

Chemical Name:4-Methyl-N-[(1S,2S)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide
CAS No.:212555-28-7
Molecular Formula:C20H26N2O4S2
Molecular Weight:422.569
Hs Code.:
European Community (EC) Number:806-427-6
DSSTox Substance ID:DTXSID70570609
Nikkaji Number:J982.864H
Wikidata:Q82458116
Mol file:212555-28-7.mol

Synonyms:212555-28-7;4-Methyl-N-[(1S,2S)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide;N,N'-((1S,2S)-Cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide);N,N'-(1S,2S)-1,2-Cyclohexanediylbis[4-methylbenzenesulfonamide];(1S,2S)-(-)-N,N'-Di-p-tosyl-1,2-cyclohexanediamine;(1S,2S)-(-)-N,N-Di-p-tosyl-1,2-cyclohexanediamine;98% pound not98% e.e.;MFCD01863518;DTXSID70570609;FIAAGQKYVFEMGC-PMACEKPBSA-N;AKOS015894766;CS-16225;CS-0093705;J-007840;J-013953;(1S,2S)-()-N,N'-Di-p-tosyl-1,2-cyclohexanediamine;(1S,2S)-(-)-N,N'-Di-p-tosyl-1,2-cyclohexanediamine, 98%;(1S,2S)-1,2-N,N'-Bis[(4-toluenesulfonyl)amino]cyclohexane;N,N'-[(1S,2S)-Cyclohexane-1,2-diyl]bis(4- methylbenzenesulfonamide);N,N'-[(1S,2S)-Cyclohexane-1,2-diyl]bis(4-methylbenzene-1-sulfonamide);(1S,2S)-(?)-N,N inverted exclamation marka-Di-p-tosyl-1,2-cyclohexanediamine

Suppliers and Price of 4-Methyl-N-[(1S,2S)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(1S,2S)-(?)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine 98%
1g
$ 95.00

ChemScene
N,N'-(1S,2S)-1,2-Cyclohexanediylbis[4-methylbenzenesulfonamide] >97.0%
5g
$ 142.00

American Custom Chemicals Corporation
(1S,2S)-(-)-N,N-DI-PARA-TOSYL-1,2-CYCLOHEXANEDIAMINE 95.00%
5MG
$ 498.96

Ambeed
N,N'-((1S,2S)-Cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide) 98%99%ee
100g
$ 356.00

Ambeed
N,N'-((1S,2S)-Cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide) 98%99%ee
25g
$ 103.00

Ambeed
N,N'-((1S,2S)-Cyclohexane-1,2-diyl)bis(4-methylbenzenesulfonamide) 98%99%ee
5g
$ 28.00

Total 14 raw suppliers

Chemical Property of 4-Methyl-N-[(1S,2S)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

Chemical Property:

Melting Point:170-173oC(lit.)
Boiling Point:591.4±60.0 °C(Predicted)
PKA:11.02±0.40(Predicted)
PSA：109.10000
Density:1.33±0.1 g/cm3(Predicted)
LogP:5.81480
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:422.13339966
Heavy Atom Count:28
Complexity:634

Purity/Quality:

98%Min ^*data from raw suppliers

(1S,2S)-(?)-N,N′-Di-p-tosyl-1,2-cyclohexanediamine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC2CCCCC2NS(=O)(=O)C3=CC=C(C=C3)C
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)N[C@H]2CCCC[C@@H]2NS(=O)(=O)C3=CC=C(C=C3)C

Technology Process of 4-Methyl-N-[(1S,2S)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide

There total 8 articles about 4-Methyl-N-[(1S,2S)-2-[(4-methylphenyl)sulfonylamino]cyclohexyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 98-59-9
p-toluenesulfonyl chloride

: 35018-62-3
(+)-(S,S)-trans-1,2-cyclohexanediamine dihydrochloride

: 212555-28-7
(S,S)-N,N'-bis(p-tolylsulfonyl)-trans-cyclohexane-1,2-diamine

Guidance literature:: With potassium carbonate; In diethyl ether; water;
DOI:10.1016/S0957-4166(99)00232-3

Reference yield: 83.0%

: 21436-03-3
(S,S)-1,2-diaminocyclohexane

: 212555-28-7
(S,S)-N,N'-bis(p-tolylsulfonyl)-trans-cyclohexane-1,2-diamine

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 ℃; for 3h; Inert atmosphere;
DOI:10.1039/c0cc05751g

Reference yield: 81.0%

: C₂₀H₂₆N₂O₃S

: 98-59-9
p-toluenesulfonyl chloride

: 212555-28-7
(S,S)-N,N'-bis(p-tolylsulfonyl)-trans-cyclohexane-1,2-diamine

Guidance literature:: C₂₀H₂₆N₂O₃S; With trichloroisocyanuric acid; sulfuric acid; In water; acetonitrile; for 16h;

p-toluenesulfonyl chloride; With triethylamine; In dichloromethane; for 16h;
DOI:10.1002/anie.201610693