2-Piperidinone, 6-phenyl-, (6R)-

Base Information

Chemical Name:2-Piperidinone, 6-phenyl-, (6R)-
CAS No.:212560-70-8
Molecular Formula:C11H13NO
Molecular Weight:175.23
Hs Code.:
DSSTox Substance ID:DTXSID50356448
Nikkaji Number:J2.477.693J
Wikidata:Q82135784
Mol file:212560-70-8.mol

Synonyms:2-Piperidinone, 6-phenyl-, (6R)-;212560-70-8;DTXSID50356448

Suppliers and Price of 2-Piperidinone, 6-phenyl-, (6R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Piperidinone, 6-phenyl-, (6R)-

Chemical Property:

PSA：29.10000
LogP:2.35660
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:185

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC(=O)C1)C2=CC=CC=C2
Isomeric SMILES:C1C[C@@H](NC(=O)C1)C2=CC=CC=C2

Technology Process of 2-Piperidinone, 6-phenyl-, (6R)-

There total 36 articles about 2-Piperidinone, 6-phenyl-, (6R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: tert-butyl (R)-2-oxo-6-phenylpiperidine-1-carboxylate

: 212560-70-8
(+)-(6R)-6-phenylpiperidin-2-one

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 3h;
DOI:10.1021/jacs.8b02752

Reference yield: 94.0%

: 4-Benzoylbutyric acid tert-butyl ester

: 212560-70-8
(+)-(6R)-6-phenylpiperidin-2-one

Guidance literature:: With Ru⁽²⁺⁾*2C₂H₃O₂^(1-)*C₇₇H₁₀₈O₆P₂; ammonium acetate; hydrogen; In 2,2,2-trifluoroethanol; at 90 ℃; for 24h; enantioselective reaction; Autoclave;
DOI:10.1021/acs.orglett.0c00669

Reference yield: 93.0%

: isopropyl 5-oxo-5-phenylpentanoate

: 212560-70-8
(+)-(6R)-6-phenylpiperidin-2-one

Guidance literature:: With Ru⁽²⁺⁾*2C₂H₃O₂^(1-)*C₇₇H₁₀₈O₆P₂; ammonium acetate; hydrogen; In 2,2,2-trifluoroethanol; at 90 ℃; for 24h; enantioselective reaction; Autoclave;
DOI:10.1021/acs.orglett.0c00669