Salicyloyl phytosphingosine

Base Information

• Chemical Name: Salicyloyl phytosphingosine
• CAS No.: 212908-67-3
• Molecular Formula: C25H43NO5
• Molecular Weight: 437.62
• European Community (EC) Number: 855-895-8
• UNII: U891J4JCNH
• Nikkaji Number: J2.489.219K
• Wikidata: Q27290849
• Mol file: 212908-67-3.mol

Synonyms:Salicyloyl phytosphingosine;Phytosphingosine slc;212908-67-3;U891J4JCNH;UNII-U891J4JCNH;Salicyloyl phytosphingosine [INCI];2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]benzamide;Benzamide, N-((1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl)-2-hydroxy-;2-hydroxy-n-((2s,3s,4r)-1,3,4-trihydroxyoctadecan-2-yl)benzamide;PhytoEFA;MICELLAROtic Cleanser;phytosphingosine salicyloyl;SuffusionPS Hypo-Allergenic;SCHEMBL8405511;DOUXO Calm Micro-emulsion Spray;Q27290849

Chemical Property of Salicyloyl phytosphingosine

Chemical Property:

• XLogP3: 6.8
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 18
• Exact Mass: 437.31412347
• Heavy Atom Count: 31
• Complexity: 448

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCC(C(C(CO)NC(=O)C1=CC=CC=C1O)O)O
• Isomeric SMILES: CCCCCCCCCCCCCC[C@H]([C@H]([C@H](CO)NC(=O)C1=CC=CC=C1O)O)O

Technology Process of Salicyloyl phytosphingosine

There total 2 articles about Salicyloyl phytosphingosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-ribo-phytosphingosine (554-62-1) + 2-hydroxy-benzoic acid ethyl ester (118-61-6) → salicyloyl-phytosphingosine (212908-67-3)

Guidance literature:

Novozym 435; In 4-methyl-2-pentanone; at 80 ℃; for 24h; Enzymatic reaction;

Reference yield:

phytosphingosine sulphate (173936-70-4) → salicyloyl-phytosphingosine (212908-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate / methanol / 2.5 h / 55 °C

2: Novozym 435 / 4-methyl-2-pentanone / 24 h / 80 °C / Enzymatic reaction

With sodium methylate; Novozym 435; In methanol; 4-methyl-2-pentanone;

upstream raw materials:

D-ribo-phytosphingosine

2-hydroxy-benzoic acid ethyl ester

phytosphingosine sulphate