Chemical Property of GGTI298 Trifluoroacetate
Chemical Property:
- Melting Point:99.5-100?°C
- PSA：173.04000
- LogP:6.47470
- Storage Temp.:−20°C
- Solubility.:DMSO: 22 mg/mL
- Hydrogen Bond Donor Count:5
- Hydrogen Bond Acceptor Count:11
- Rotatable Bond Count:11
- Exact Mass:593.21712685
- Heavy Atom Count:41
- Complexity:745
- Purity/Quality:
-
98%,99%, *data from raw suppliers
GGTI 298 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC(C)CC(C(=O)OC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC3=CC=CC=C32.C(=O)(C(F)(F)F)O
- Isomeric SMILES:CC(C)C[C@@H](C(=O)OC)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC3=CC=CC=C32.C(=O)(C(F)(F)F)O
-
Uses
GGTI 298 is a CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I (GGTase I). It has been shown to arrest human tumor cells and induce apoptosis.
