6-Amino-9-(4-fluorobenzyl)purine

Base Information

Chemical Name:6-Amino-9-(4-fluorobenzyl)purine
CAS No.:213528-06-4
Molecular Formula:C12H10FN5
Molecular Weight:243.243
Hs Code.:
ChEMBL ID:CHEMBL426037
DSSTox Substance ID:DTXSID90465846
Wikidata:Q82292108
Mol file:213528-06-4.mol

Synonyms:213528-06-4;9-(4-Fluorobenzyl)-9H-purin-6-amine;6-Amino-9-(4-fluorobenzyl)purine;9-[(4-fluorophenyl)methyl]-9H-purin-6-amine;CHEMBL426037;SCHEMBL6659204;DTXSID90465846;WSFGAOJQQBTCHL-UHFFFAOYSA-N;AKOS012923785

Suppliers and Price of 6-Amino-9-(4-fluorobenzyl)purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 6-Amino-9-(4-fluorobenzyl)purine

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:243.09202350
Heavy Atom Count:18
Complexity:282

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CN2C=NC3=C(N=CN=C32)N)F

Technology Process of 6-Amino-9-(4-fluorobenzyl)purine

There total 3 articles about 6-Amino-9-(4-fluorobenzyl)purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 112088-75-2
6-chloro-9-(4-fluorobenzyl)purine

: 213528-06-4
6-Amino-9-(4-fluorobenzyl)purine

Guidance literature:: With ammonia; In methanol; at 90 ℃;
DOI:10.1021/jm0408767

Reference yield:

: 87-42-3
6-chloropurine

: 213528-06-4
6-Amino-9-(4-fluorobenzyl)purine

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / K₂CO₃ / dimethylformamide / 20 °C

2: 76 percent / NH₃ / methanol / 90 °C

With ammonia; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0408767

Reference yield:

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 213528-06-4
6-Amino-9-(4-fluorobenzyl)purine

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / K₂CO₃ / dimethylformamide / 20 °C

2: 76 percent / NH₃ / methanol / 90 °C

With ammonia; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0408767