2-Phenyl-5-pyridin-3-yl-1,3,4-oxadiazole

Base Information

Chemical Name:2-Phenyl-5-pyridin-3-yl-1,3,4-oxadiazole
CAS No.:21398-08-3
Molecular Formula:C13H9N3O
Molecular Weight:223.234
Hs Code.:
DSSTox Substance ID:DTXSID80353420
Nikkaji Number:J1.094.621B
Wikidata:Q82131010
ChEMBL ID:CHEMBL1276290
Mol file:21398-08-3.mol

Synonyms:21398-08-3;2-phenyl-5-pyridin-3-yl-1,3,4-oxadiazole;3-(5-phenyl-1,3,4-oxadiazol-2-yl)pyridine;2-phenyl-5-(pyridin-3-yl)-1,3,4-oxadiazole;Pyridine, 3-(5-phenyl-1,3,4-oxadiazol-2-yl)-;HMS1480C13;ChemDiv3_002521;Cambridge id 5481930;F1424-0231;CHEMBL1276290;SCHEMBL13197417;DTXSID80353420;STK246490;AKOS001220147;CCG-109767;AB00086675-01;AH-034/04886008;2-PHENYL-5-(3-PYRIDYL)-1,3,4-OXADIAZOLE;BRD-K40551492-001-01-2;Z50150579

Suppliers and Price of 2-Phenyl-5-pyridin-3-yl-1,3,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Phenyl-5-pyridin-3-yl-1,3,4-oxadiazole

Chemical Property:

Melting Point:121.5-122.0 °C(Solv: toluene (108-88-3); ligroine (8032-32-4))
Boiling Point:407.5±47.0 °C(Predicted)
PKA:1.95±0.12(Predicted)
PSA：51.81000
Density:1.223±0.06 g/cm3(Predicted)
LogP:2.79860
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:223.074561919
Heavy Atom Count:17
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN=C(O2)C3=CN=CC=C3

Technology Process of 2-Phenyl-5-pyridin-3-yl-1,3,4-oxadiazole

There total 23 articles about 2-Phenyl-5-pyridin-3-yl-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 553-53-7
Nicotinic acid hydrazide

: 65-85-0,8013-63-6
benzoic acid

: 21398-08-3
3-(5-phenyl-1,3,4-oxadiazol-2-yl)pyridine

Guidance literature:: With trichlorophosphate; for 0.2h; microwave irradiation;
DOI:10.1016/j.bmc.2005.03.012

Reference yield: 89.0%

: 626-55-1,163928-56-1
3-Bromopyridine

: MIDA (5-phenyl-1,3,4-oxadiazol-2-yl)boronate

: 21398-08-3
3-(5-phenyl-1,3,4-oxadiazol-2-yl)pyridine

Guidance literature:: With chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); copper diacetate; potassium carbonate; In tert-Amyl alcohol; N,N-dimethyl-formamide; at 100 ℃; for 16h; Inert atmosphere;
DOI:10.1002/anie.201907486