2,4,6-Tri(propan-2-yl)aniline

Base Information

• Chemical Name: 2,4,6-Tri(propan-2-yl)aniline
• CAS No.: 21524-36-7
• Molecular Formula: C15H25N
• Molecular Weight: 219.37
• European Community (EC) Number: 800-008-1
• DSSTox Substance ID: DTXSID801290939
• Nikkaji Number: J2.152.416F
• Mol file: 21524-36-7.mol

Synonyms:2,4,6-triisopropylaniline;21524-36-7;2,4,6-tri(propan-2-yl)aniline;benzenamine, 2,4,6-tris(1-methylethyl)-;EC 800-008-1;ChemDiv3_001152;SCHEMBL3440745;Aniline, 2,4,6-triisopropyl-;(2,4,6-triisopropylphenyl)amine;DTXSID801290939;HMS1476E08;2,4,6-tris(propan-2-yl)aniline;2,4,6-Tris(1-methylethyl)benzenamine;IDI1_020118;NCGC00172938-01;EN300-10848484;BRD-K91409934-003-01-3

Chemical Property of 2,4,6-Tri(propan-2-yl)aniline

Chemical Property:

• Boiling Point: 158-160 °C(Press: 18 Torr)
• PSA: 26.02000
• Density: 0.9107 g/cm3(Temp: 25 °C)
• LogP: 5.22020
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 219.198699802
• Heavy Atom Count: 16
• Complexity: 190

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)C1=CC(=C(C(=C1)C(C)C)N)C(C)C

Technology Process of 2,4,6-Tri(propan-2-yl)aniline

There total 6 articles about 2,4,6-Tri(propan-2-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,3,5-triisopropyl-2-nitrobenzene (13402-31-8) → 2,4,6-triisopropylaniline (21524-36-7)

Guidance literature:

With hydrazine hydrate; palladium on activated charcoal; In ethanol; for 18h; Heating;

DOI:10.1016/j.jorganchem.2004.11.029

Reference yield: 55.0%

1,3,5-triisopropyl benzene (717-74-8) → 2,4,6-triisopropylaniline (21524-36-7)

Guidance literature:

With tert-butyl N-tosyloxycarbamate; at 20 ℃; for 36h; chemoselective reaction;

DOI:10.1002/adsc.202100236

Reference yield: 42.0%

1-amino-2,4,6-triisopropylbenzene hydrochloride → 2,4,6-triisopropylaniline (21524-36-7)

Guidance literature:

With sodium hydroxide; In water; pentane; Inert atmosphere; Schlenk technique;

DOI:10.1039/c6dt00229c

upstream raw materials:

propene

aniline

1,3,5-triisopropyl-2-nitrobenzene

isopropyl alcohol

Downstream raw materials:

acetic acid-(2,4,6-triisopropyl-anilide)

2,4,6-triisopropyl-3-nitro-aniline

2,4,6-triisopropyl-N,N-dimethyl-aniline

1-fluoro-2,4,6-triisopropylbenzene