1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-(2-ethyl-1H-imidazol-1-yl)phenyl ]-3-(trifluoromethyl)-, mono(trifluoroacetate)

Base Information

Chemical Name:1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-(2-ethyl-1H-imidazol-1-yl)phenyl ]-3-(trifluoromethyl)-, mono(trifluoroacetate)
CAS No.:218299-37-7
Molecular Formula:C₂HF₃O₂*C₂₃H₁₈F₃N₇O₂
Molecular Weight:595.461
Hs Code.:

1H-Pyrazole-5-carboxamide,
1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-(2-ethyl-1H-imidazol-1-yl)phenyl
]-3-(trifluoromethyl)-, mono(trifluoroacetate)

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Chemical Property of 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-(2-ethyl-1H-imidazol-1-yl)phenyl ]-3-(trifluoromethyl)-, mono(trifluoroacetate)

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Technology Process of 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-(2-ethyl-1H-imidazol-1-yl)phenyl ]-3-(trifluoromethyl)-, mono(trifluoroacetate)

There total 1 articles about 1H-Pyrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[4-(2-ethyl-1H-imidazol-1-yl)phenyl ]-3-(trifluoromethyl)-, mono(trifluoroacetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 754193-45-8
2-(3-cyano-4-fluoro-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carbonyl chloride

: 4-(2-ethyl-1H-imidazol-1-yl)benzenamine

: 76-05-1
trifluoroacetic acid

: 127-06-0
acetone oxime

: 218299-37-7
1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-5-[[4-(2'-ethylimidazol-1'-yl)phenyl]aminocarbonyl]pyrazole TFA salt

Guidance literature:: 2-(3-cyano-4-fluoro-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carbonyl chloride; 4-(2-ethyl-1H-imidazol-1-yl)benzenamine; With dmap;

acetone oxime; With sodium t-butanolate;

trifluoroacetic acid; With hydrogenchloride; more than 3 stages;