1H-Tetrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(1-pyrrolidinylcarbonyl) phenyl]-, mono(trifluoroacetate)

Base Information

Chemical Name:1H-Tetrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(1-pyrrolidinylcarbonyl) phenyl]-, mono(trifluoroacetate)
CAS No.:218299-71-9
Molecular Formula:C₂HF₃O₂*C₂₀H₁₇FN₈O₃
Molecular Weight:550.429
Hs Code.:
Mol file:218299-71-9.mol

1H-Tetrazole-5-carboxamide,
1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(1-pyrrolidinylcarbonyl)
phenyl]-, mono(trifluoroacetate)

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Tetrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(1-pyrrolidinylcarbonyl) phenyl]-, mono(trifluoroacetate)

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Technology Process of 1H-Tetrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(1-pyrrolidinylcarbonyl) phenyl]-, mono(trifluoroacetate)

There total 1 articles about 1H-Tetrazole-5-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-N-[2-fluoro-4-(1-pyrrolidinylcarbonyl) phenyl]-, mono(trifluoroacetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76-05-1
trifluoroacetic acid

: 209960-85-0
(4-amino-3-fluorophenyl)pyrrolidin-1-ylmethanone

: 218301-75-8
ethyl 1-(3-cyano-4-fluorophenyl)-5-tetrazole carboxylate

: 127-06-0
acetone oxime

: 218299-71-9
1-(3'-aminobenzisoxazol-5'-yl)-5-[(2-fluoro-4-(N-pyrrolidinocarbonyl)phenyl)aminocarbonyl]tetrazole trifluoroacetic acid salt

Guidance literature:: (4-amino-3-fluorophenyl)pyrrolidin-1-ylmethanone; ethyl 1-(3-cyano-4-fluorophenyl)-5-tetrazole carboxylate; With trimethylaluminum;

acetone oxime; With potassium tert-butylate;

trifluoroacetic acid; With hydrogenchloride; more than 3 stages;