Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate

Base Information

Chemical Name:Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate
CAS No.:70705-33-8
Molecular Formula:C₁₁H₁₂N₂O₂
Molecular Weight:204.228
Hs Code.:2933990090
DSSTox Substance ID:DTXSID60357683
Wikidata:Q72475960
ChEMBL ID:CHEMBL1327155
Mol file:70705-33-8.mol

Synonyms:ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate;70705-33-8;7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester;7-Methyl-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester;MFCD02187526;ethyl 7-methylimidazo(1,2-a)pyridine-2-carboxylate;Oprea1_426344;Oprea1_479972;MLS000718464;ethyl 7-methylH-imidazo[1,2-a]pyridine-2-carboxylate;SCHEMBL1445451;CHEMBL1327155;DTXSID60357683;AVYYNZWWGNNXRW-UHFFFAOYSA-N;HMS2691I16;STK510244;AKOS000669633;AB11567;CS-W002932;SMR000290732;SY014152;AM20070209;FT-0680299;EN300-232135;3R-0655;A836970;J-521227;(R)-[1-(4-Aminophenyl)ethyl]carbamicacidtert-butylester;7-methyl-imidazo[1,2-a]pyridine-2-carboxylic acidethyl ester

Suppliers and Price of Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate
100mg
$ 305.00

TRC
Ethyl7-methylimidazo[1,2-a]pyridine-2-carboxylate
250mg
$ 55.00

SynQuest Laboratories
Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate
5 g
$ 168.00

SynChem
7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester 95+%
1 g
$ 100.00

SynChem
7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester 95+%
5 g
$ 295.00

SynChem
7-Methylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester 95+%
10 g
$ 485.00

Matrix Scientific
Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate >95%
1g
$ 454.00

Matrix Scientific
Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate >95%
500mg
$ 362.00

Crysdot
Ethyl7-methylimidazo[1,2-a]pyridine-2-carboxylate 95+%
5g
$ 149.00

Crysdot
Ethyl7-methylimidazo[1,2-a]pyridine-2-carboxylate 95+%
1g
$ 49.00

Total 32 raw suppliers

Chemical Property of Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate

Chemical Property:

Melting Point:126-129oC
Refractive Index:1.585
PKA:3.92±0.50(Predicted)
PSA：43.60000
Density:1.2 g/cm³
LogP:1.81940
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:204.089877630
Heavy Atom Count:15
Complexity:245

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN2C=CC(=CC2=N1)C

Technology Process of Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate

There total 2 articles about Ethyl 7-methylimidazo[1,2-a]pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 695-34-1
2-Amino-4-methylpyridine

: 70-23-5
ethyl Bromopyruvate

: 70705-33-8
ethyl 7-methylimidazo<1,2-a>pyridine-2-carboxylate

Guidance literature:: In ethanol; for 5h; Heating;
DOI:10.1007/s11164-012-0561-6

Reference yield:

: 70705-33-8
ethyl 7-methylimidazo<1,2-a>pyridine-2-carboxylate

Guidance literature:: Brom-brenztraubensaeure-ethylester, 2-Amino-4-methylpyridin;

Reference yield:

: 70705-33-8
ethyl 7-methylimidazo<1,2-a>pyridine-2-carboxylate

: 3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-7-methyl-2H-2,4,4b,9-tetraaza-fluoren-1-one

Guidance literature:: Multi-step reaction with 7 steps

1: HNO₃; H₂SO₄ / 2 h / -5 - 0 °C

2: aq. NH₃ / tetrahydrofuran / 20 °C

3: H₂ / Pd/C / 50 °C

4: pyridine; DMAP / CH₂Cl₂

5: KOt-Bu / 2-methyl-propan-2-ol / Heating

6: chlorosulfonic acid / 3 h / 0 - 5 °C

7: Et₃N / CHCl₃ / 20 °C

With pyridine; chlorosulfonic acid; dmap; ammonium hydroxide; sulfuric acid; potassium tert-butylate; hydrogen; nitric acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; chloroform; tert-butyl alcohol;
DOI:10.1016/j.bmcl.2005.03.102