10H-Phenoxazine-10-propanoic acid

Base Information

• Chemical Name: 10H-Phenoxazine-10-propanoic acid
• CAS No.: 21977-42-4
• Molecular Formula: C₁₅H₁₃NO₃
• Molecular Weight: 255.273
• DSSTox Substance ID: DTXSID60401756
• Nikkaji Number: J2.025.607I
• Wikidata: Q82204988
• Mol file: 21977-42-4.mol

Synonyms:21977-42-4;10H-Phenoxazine-10-propanoic acid;3-(10H-PHENOXAZIN-10-YL)PROPANOIC ACID;3-phenoxazin-10-ylpropanoic Acid;3-(10-Phenoxazinyl)propanoic Acid;SCHEMBL179725;DTXSID60401756;MFCD05022207;SY268397;CS-0120960

Chemical Property of 10H-Phenoxazine-10-propanoic acid

Chemical Property:

• PSA: 49.77000
• LogP: 3.47010
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 255.08954328
• Heavy Atom Count: 19
• Complexity: 311

Purity/Quality:

99% ^*data from raw suppliers

10H-Phenoxazine-10-propanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)N(C3=CC=CC=C3O2)CCC(=O)O

Technology Process of 10H-Phenoxazine-10-propanoic acid

There total 4 articles about 10H-Phenoxazine-10-propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenoxazin-10-yl-propionitrile (3921-18-4) → 10-(2-Carboxy-aethyl)-phenoxazin (21977-42-4)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/jo01093a019

Reference yield:

phenoxazine (135-67-1) → 10-(2-Carboxy-aethyl)-phenoxazin (21977-42-4)

Guidance literature:

Multi-step reaction with 2 steps

1: benzyl-trimethyl-ammonium methylate

2: ethanolic NaOH

With sodium hydroxide; benzyltrismethylammonium methoxide;

DOI:10.1021/jo01093a019

Reference yield:

3-phenoxazin-10-yl-propionamide (27874-60-8) → 10-(2-Carboxy-aethyl)-phenoxazin (21977-42-4)

Guidance literature:

With hydrogenchloride; In methanol; for 1.5h; Heating;

upstream raw materials:

3-phenoxazin-10-yl-propionitrile

3-phenoxazin-10-yl-propionamide

phenoxazine