3-(4-Aminophenyl)-1,3-oxazolidin-2-one

Base Information

Chemical Name:3-(4-Aminophenyl)-1,3-oxazolidin-2-one
CAS No.:22036-26-6
Molecular Formula:C9H10N2O2
Molecular Weight:178.191
Hs Code.:2934999090
European Community (EC) Number:827-295-6
Mol file:22036-26-6.mol

Synonyms:3-(4-aminophenyl)-1,3-oxazolidin-2-one;22036-26-6;3-(4-aminophenyl)oxazolidin-2-one;SCHEMBL1377738;DDCWSJXZZUOJRT-UHFFFAOYSA-N;MFCD11167814;STK505858;3-(4-aminophenyl)-oxazolidin-2-one;AKOS005172302;DB-293616;CS-0250701;EN300-51935;G22888;3-(4-AMINOPHENYL)-1,3-OXAZOLAN-2-ONE;A925083;Z336028106

Suppliers and Price of 3-(4-Aminophenyl)-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(4-Aminophenyl)-1,3-oxazolidin-2-one
100mg
$ 140.00

TRC
3-(4-Aminophenyl)-1,3-oxazolidin-2-one
500mg
$ 470.00

Matrix Scientific
3-(4-Aminophenyl)-1,3-oxazolidin-2-one
1g
$ 462.00

Matrix Scientific
3-(4-Aminophenyl)-1,3-oxazolidin-2-one
500mg
$ 300.00

Crysdot
3-(4-Aminophenyl)oxazolidin-2-one 97%
5g
$ 668.00

American Custom Chemicals Corporation
3-(4-AMINOPHENYL)-1,3-OXAZOLIDIN-2-ONE 95.00%
1G
$ 852.55

American Custom Chemicals Corporation
3-(4-AMINOPHENYL)-1,3-OXAZOLIDIN-2-ONE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
3-(4-AMINOPHENYL)-1,3-OXAZOLIDIN-2-ONE 95.00%
2.5G
$ 1227.82

AK Scientific
3-(4-Aminophenyl)-1,3-oxazolidin-2-one
10g
$ 2387.00

AK Scientific
3-(4-Aminophenyl)-1,3-oxazolidin-2-one
5g
$ 1650.00

Total 7 raw suppliers

Chemical Property of 3-(4-Aminophenyl)-1,3-oxazolidin-2-one

Chemical Property:

PSA：55.56000
LogP:1.87160
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:178.074227566
Heavy Atom Count:13
Complexity:200

Purity/Quality:

97% ^*data from raw suppliers

3-(4-Aminophenyl)-1,3-oxazolidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(=O)N1C2=CC=C(C=C2)N
Uses 3-(4-Aminophenyl)-1,3-oxazolidin-2-one is a reactant used in the preparation of N-phenyl-4,5-dibromopyrrolamides and N-phenylindolamides which can act as ATPase inhibitors of DNA gyrase.

Technology Process of 3-(4-Aminophenyl)-1,3-oxazolidin-2-one

There total 5 articles about 3-(4-Aminophenyl)-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 5198-52-7
3-(4-nitrophenyl)-2-oxazolidinone

: 22036-26-6
3-(4-aminophenyl)-1,3-oxazolidin-2-one

Guidance literature:: With palladium on activated charcoal; hydrogen; In tetrahydrofuran; at 20 ℃; for 5h;
DOI:10.1016/j.ejmech.2016.03.079

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 22036-26-6
3-(4-aminophenyl)-1,3-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / dioxane

2: aq. KOH / ethanol / 0.07 h / 60 °C

3: H₂ / Pd-C / tetrahydrofuran / 2206.5 - 2942.03 Torr / Ambient temperature

With potassium hydroxide; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; ethanol;

Reference yield:

: 60480-06-0
1-chloro-2-(4-nitro-phenylcarbamoyloxy)-ethane

: 22036-26-6
3-(4-aminophenyl)-1,3-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: aq. KOH / ethanol / 0.07 h / 60 °C

2: H₂ / Pd-C / tetrahydrofuran / 2206.5 - 2942.03 Torr / Ambient temperature

With potassium hydroxide; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;