3,4-Dihydro-2--1-naphthylessigsaeure

Base Information

• Chemical Name: 3,4-Dihydro-2--1-naphthylessigsaeure
• CAS No.: 102018-45-1
• Molecular Formula: C₁₉H₁₈O₂
• Molecular Weight: 278.351
• Mol file: 102018-45-1.mol

Synonyms:

Chemical Property of 3,4-Dihydro-2--1-naphthylessigsaeure

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-Dihydro-2--1-naphthylessigsaeure

There total 4 articles about 3,4-Dihydro-2--1-naphthylessigsaeure which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-methylphenyl)acetonitrile (2947-61-7) → 3,4-Dihydro-2--1-naphthylessigsaeure (102018-45-1)

Guidance literature:

Multi-step reaction with 4 steps

1: (i) NaNH₂, (ii) /BRN= 385969/

2: aq. AcOH, H₂SO₄

3: HF

4: (i) Zn, I₂, (ii) aq. KOH

With sulfuric acid; hydrogen fluoride; acetic acid;

DOI:10.1039/jr9610000212

Reference yield:

4-Phenyl-2--buttersaeure (108974-22-7) → 3,4-Dihydro-2--1-naphthylessigsaeure (102018-45-1)

Guidance literature:

Multi-step reaction with 2 steps

1: HF

2: (i) Zn, I₂, (ii) aq. KOH

With hydrogen fluoride;

DOI:10.1039/jr9610000212

Reference yield:

3-Phenyl-1-<4-tolyl>-propylcyanid (92615-41-3) → 3,4-Dihydro-2--1-naphthylessigsaeure (102018-45-1)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. AcOH, H₂SO₄

2: HF

3: (i) Zn, I₂, (ii) aq. KOH

With sulfuric acid; hydrogen fluoride; acetic acid;

DOI:10.1039/jr9610000212

upstream raw materials:

2-(p-tolyl)-3,4-dihydronaphthalen-1(2H)-one

ethyl bromoacetate

(4-methylphenyl)acetonitrile

3-Phenyl-1-<4-tolyl>-propylcyanid