5-chloro-3-phenyl-1H-indole

Base Information

Chemical Name:5-chloro-3-phenyl-1H-indole
CAS No.:22072-89-5
Molecular Formula:C14H10ClN
Molecular Weight:227.693
Hs Code.:
DSSTox Substance ID:DTXSID70461967
Nikkaji Number:J1.710.519A
Wikidata:Q82286430
Mol file:22072-89-5.mol

Synonyms:5-chloro-3-phenyl-1H-indole;22072-89-5;5-chlor-3-phenyl-1H-indole;SCHEMBL9273186;DTXSID70461967;QWCNAXBXVVZXGZ-UHFFFAOYSA-N;FT-0735217

Suppliers and Price of 5-chloro-3-phenyl-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-chloro-3-phenyl-1H-indole

Chemical Property:

PSA：15.79000
LogP:4.48830
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:1
Exact Mass:227.0501770
Heavy Atom Count:16
Complexity:237

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CNC3=C2C=C(C=C3)Cl

Technology Process of 5-chloro-3-phenyl-1H-indole

There total 25 articles about 5-chloro-3-phenyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 122-78-1
phenylacetaldehyde

: 1073-69-4
N-4-chlorophenylhydrazine

: 22072-89-5
5-Chloro-3-phenyl-1H-indole

Guidance literature:: phenylacetaldehyde; N-4-chlorophenylhydrazine; at 20 - 100 ℃; for 1.5h;

With zinc(II) chloride; In ethanol; for 24h; Reflux;
DOI:10.1021/acs.joc.8b01146

Reference yield: 78.0%

: 591-50-4
iodobenzene

: 17422-32-1
5-chloro-1H-indole

: 22072-89-5
5-Chloro-3-phenyl-1H-indole

Guidance literature:: With palladium diacetate; lithium hexamethyldisilazane; In toluene; at 120 ℃; for 16h; Catalytic behavior;
DOI:10.1021/acscatal.9b04864