4-Chloro-7-nitro-2,1,3-benzothiadiazole

Base Information

• Chemical Name: 4-Chloro-7-nitro-2,1,3-benzothiadiazole
• CAS No.: 2207-29-6
• Molecular Formula: C6H2ClN3O2S
• Molecular Weight: 215.61700
• Hs Code.: 2934999090
• Mol file: 2207-29-6.mol

Synonyms:4-Nitro-7-chlor-2,1,3-benzothiadiazol;4-Chloro-7-nitro-benz-2,1,3-thiadiazol;4-chloro-7-nitro-2,1,3-benzothiadiazole;4-Chlor-7-nitro-2,1,3-benzothiadiazol;

Chemical Property of 4-Chloro-7-nitro-2,1,3-benzothiadiazole

Chemical Property:

• PSA: 99.84000
• LogP: 2.77610
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-7-nitro-2,1,3-benzothiadiazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Chloro-7-nitro-2,1,3-benzothiadiazole

There total 6 articles about 4-Chloro-7-nitro-2,1,3-benzothiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-chloro-6-nitrobenzene-1,2-diamine → 4-chloro-7-nitrobenzo[c][1,2,5]thiadiazole (2207-29-6)

Guidance literature:

With N-phenylsulfinylamine; In toluene; at 120 ℃; for 5h;

DOI:10.1002/anie.201900465

Reference yield:

4-Chlor-benz<2,1,3>thiadiazol (2207-28-5) → 4-chloro-7-nitrobenzo[c][1,2,5]thiadiazole (2207-29-6)

Guidance literature:

With sodium nitrate; sulfuric acid; at 95 - 100 ℃;

DOI:10.1007/BF00468340

Reference yield:

2,3-diaminochlorobenzene (21745-41-5) → 4-chloro-7-nitrobenzo[c][1,2,5]thiadiazole (2207-29-6)

Guidance literature:

Multi-step reaction with 4 steps

1: selenium(IV) oxide / ethanol / 0.5 h / Reflux

2: sulfuric acid; nitric acid / 0.25 h / 0 °C

3: hydrogen iodide; water; hydrogenchloride / 1 h / 20 °C

4: N-phenylsulfinylamine / toluene / 5 h / 120 °C

With hydrogenchloride; selenium(IV) oxide; sulfuric acid; water; hydrogen iodide; nitric acid; N-phenylsulfinylamine; In ethanol; toluene;

DOI:10.1002/anie.201900465

upstream raw materials:

4-Chlor-benz<2,1,3>thiadiazol

2,3-diaminochlorobenzene

4-chlorobenzo[c][1,2,5]selenadiazole

Downstream raw materials:

4-Chlor-7-amino-benz<2.1.3>thiodiazol