4-Aminopentan-1-ol

Base Information

• Chemical Name: 4-Aminopentan-1-ol
• CAS No.: 927-55-9
• Molecular Formula: C5H13NO
• Molecular Weight: 103.164
• Hs Code.: 2922199090
• European Community (EC) Number: 213-151-4
• NSC Number: 1095
• DSSTox Substance ID: DTXSID401316181
• Nikkaji Number: J298.496B
• Mol file: 927-55-9.mol

Synonyms:4-Aminopentan-1-ol;927-55-9;4-Amino-1-pentanol;1-Pentanol, 4-amino-;4-Amino-1-pentanol-d4;EINECS 213-151-4;1-Pentanol,4-amino-;NSC1095;NSC 1095;SCHEMBL362003;DTXSID401316181;NSC-1095;MFCD16251198;AKOS006339189;AT20758;SB84011;FT-0661992;EN300-104358;A852186;Z1203578676

Chemical Property of 4-Aminopentan-1-ol

Chemical Property:

• Vapor Pressure: 0.369mmHg at 25°C
• Melting Point: 32°C
• Refractive Index: 1.449
• Boiling Point: 174.7 °C at 760 mmHg
• PKA: 15.12±0.10(Predicted)
• Flash Point: 59.4 °C
• PSA: 46.25000
• Density: 0.915 g/cm³
• LogP: 0.80640
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 103.099714038
• Heavy Atom Count: 7
• Complexity: 39.1

Purity/Quality:

99%, ^*data from raw suppliers

4-Amino-1-pentanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CCCO)N

Technology Process of 4-Aminopentan-1-ol

There total 9 articles about 4-Aminopentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

5-Hydroxy-2-pentanone (1071-73-4) → (±)-4-amino-1-pentanol (927-55-9)

Guidance literature:

With ammonium hydroxide; hydrogen; In ethanol; water; at 80 ℃; for 2h; under 15001.5 Torr; Autoclave;

DOI:10.1039/d0nj04962j

Reference yield: 58.0%

methyl 4-nitropentanoate (10312-37-5) → (±)-4-amino-1-pentanol (927-55-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

Reference yield:

5-hydroxypentan-2-one oxime (57669-08-6) → (±)-4-amino-1-pentanol (927-55-9)

Guidance literature:

With nickel; at 60 - 75 ℃; under 95000 Torr; Hydrogenation;

upstream raw materials:

5-Hydroxy-2-pentanone

5-hydroxypentan-2-one oxime

4-nitro-valeric acid ethyl ester

pentyl hydroperoxide

Downstream raw materials:

N-(4-hydroxy-1-methyl-butyl)-phthalimide

N-(4-bromo-1-methyl-butyl)-phthalimide

4-(7-chloro-quinolin-4-ylamino)-pentan-1-ol

Cletoquine

Refernces

• 1、 Zhang, Jia,Yang, Jian,Tian, Junying,Liu, Hailong,Li, Xuemei,Fang, Weiguo,Hu, Xun,Xia, Chungu,Chen, Jing,Huang, Zhiwei. "Reductive amination of bio-based 2-hydroxytetrahydropyran to 5-Amino-1-pentanol over nano-Ni-Al2O3catalysts". supporting information. p. 4236 - 4245. Retrieved 2021/03/15.
• 2、 Cekovic, Zivorad,Cvetkovic, Milutin. "FUNCTIONALIZATION OF THE δ-CARBON ATOM BY THE FERROUS ION INDUCED DECOMPOSITION OF ALKYL HYDROPEROXIDES IN THE PRESENCE OF CUPRIC SALTS". . p. 3791 - 3794. Retrieved 2007/10/02.